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2023, Number 2

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Gaceta Médica Espirituana 2023; 25 (2)

Macroscopic hematuria as an initial sign of primary urethral cancer. Case report

Marín VK, Roca RD, Peña FLM, Pérez SYR, Ibargollín UR, Rondón MEA
Full text How to cite this article

Language: Spanish
References: 8
Page: 1-6
PDF size: 217.36 Kb.


Key words:

Primary urethral cancer, urothelial carcinoma, prostate, urethra, hematuria, urethral neoplasms, urologic neoplasms.

ABSTRACT

Background: Primary urethral cancer is defined as a tumor whose first lesion is located in the urethra; is very uncommon, represents less than 1% of malignant tumors and 5% of malignant tumors of the urinary system. The extension of this process to the prostate gland creates obstructive and irritative urinary symptoms and acute conditions such as macroscopic hematuria.
Objective: To present the case of a patient with primary urethral carcinoma in its urothelial variety with macroscopic hematuria as clinical presentation.
Case presentation: Clinical case of a 75-year-old male patient, with macroscopic hematuria as a clinical presentation of primary cancer of the urethra in its urothelial variety, diagnosed anatomopathologically during the hematuria study.
Conclusions: The case presented alerts the scientific community that the diagnosis of primary urethral cancer should be considered in patients with macroscopic hematuria in the absence of obstructive or irritative urologic manifestations, although it is a rare sign as clinical presentation of this disease.


REFERENCES

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  2. Krukowski J, Czajkowski M, Kłącz J, Wawrzaszek O, Gołębiewska M, Matuszewski M. Primary urethralcarcinoma – unexpected cause of urethral stricture. Case report and review of the literature. MedicalUltrasonography [Internet]. 2019 [cited 2022 Dec 18];21(4):494-6. Available from:https://www.medultrason.ro/medultrason/index.php/medultrason/article/view/2015/1445

  3. Wenzel M, Deuker M, Nocera L, Collà Ruvolo C, Tian Z, Shariat SF, et al. Comparison between urothelial andnon-urothelial urethral cancer. Front Oncol [Internet]. 2020 [cited 2022 Dec 18];10. Available from:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7880052/pdf/fonc-10-629692.pdf

  4. Mano R, Vertosick EA, Sarcona J, Sjoberg DD, Benfante NE, Donahue TF, et al. Primary urethral cancer:treatment patterns and associated outcomes. BJU Int [Internet]. 2020 [cited 2022 Dec 18];126(3):359-66. Availablefrom: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7483343/pdf/nihms-1599094.pdf

  5. Gakis G, Bruins HM, Cathomas R, Compérat EM, Cowan NC, van der Heijden AG, et al. European Associationof Urology Guidelines on Primary Urethral Carcinoma-2020 Update. Eur Urol Oncol [Internet]. 2020 [cited 2022Dec 18];3(4):424-32. Available from:https://www.researchgate.net/publication/342505948_European_Association_of_Urology_Guidelines_on_Primary_Urethral_Carcinoma-2020_Update

  6. Farrell MR, Xu JT, Vanni AJ. Current perspectives on the diagnosis and management of primary urethral cancer:a systematic review. Res Rep Urol [Internet]. 2021 [cited 2022 Dec 18];13:325-34. Available from:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8180270/pdf/rru-13-325.pdf

  7. Zhang M, Adeniran AJ, Vikram R, Tamboli P, Pettaway C, Bondaruk J, et al. Carcinoma of the urethra. HumPathol [Internet]. 2018 [cited 2022 Dec 18];72:35-44. Available from:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5975388/pdf/nihms900596.pdf

  8. Zeng J, Wang S, Zhong L, Huang Z, Zeng Y, Wu S, et al. Unusual Features of Clear Cell Adenocarcinoma ofthe Female Urethra: A Case Report and Literature Review. J Clin Med Res [Internet]. 2018 [cited 2022 Dec18];10(8):665-7. Access: 08/09/2021. Available from:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031250/pdf/jocmr-10-665.pdf




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