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2025, Number 4

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Rev Mex Traspl 2025; 14 (4)

Creatinine behavior in kidney donors, one-year follow-up

Bautista-Olayo R, Espinoza-Pérez R, Cedillo-Galindo H, Cancino-López JD, Morinelli-Astorquizaga MA, Caltzoncin-Aguilera L, Guerrero-Rosales AO, Flores-Gama F, Bravo-León J, Hernández-Rivera JCH

Language: Spanish
References: 17
Page: 153-158
PDF size: 330.05 Kb.


ABSTRACT

Introduction: kidney donation involves immediate and long-term risks, mainly in kidney function. Factors related to function are widely described; the sex of the donor does not seem to influence this, but this is poorly described. The objective of this study was to determine the behavior of creatinine in men and women with a one-year follow-up. Material and methods: a review of kidney donor records from 2016 to 2021 was conducted to collect their creatinine values before donation, as well as one, three, six and 12 months after the surgical event. Creatinine levels are compared in men and women; median and interquartile range (IQR) (quartiles 25-75) are obtained. SPSS 27 software was used. Results: 492 records of living kidney donors were analyzed: 258 (52.44%) women and 234 (47.56%) men. The median age was 39 years (IQR 29-47). The median creatinine level was 0.76 mg/dL (IQR 0.64-0.90 mg/dL) before donation, 1.13 mg/dL (IQR 0.96-1.32) at three months, 1.09 mg/dL (IQR 0.94-1.30) at six months, 1.10 mg/dL (0.94-1.27) at nine months, and 1.12 mg/dL (IQR 0.95-1.29) at 12 months. At 1 year, creatinine increased by 38.88% (0.72-1.00 mg/dL) in women and 46.66% (0.90-1.32 mg/dL) in men. Conclusions: a clear trend of creatinine elevation after surgery can be observed, which never returns to baseline; this elevation is observed from the first month and remains constant for up to 12 months.


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