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2025, Number 4

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Cir Plast 2025; 35 (4)

Adult Still's disease associated with alloplastic implants for breast cancer: case report and narrative review of the literature

Said-Lemus FM, Sánchez-Forgach ER, Sánchez-Rodríguez A, Camacho-Limas CP
Full text How to cite this article 10.35366/122089

DOI

DOI: 10.35366/122089
URL: https://dx.doi.org/10.35366/122089

Language: Spanish
References: 16
Page: 208-213
PDF size: 351.58 Kb.


Key words:

adult Still is disease, autoimmune inflammatory syndrome induced by adjuvants, breast implants, autoimmunity, post-mastectomy reconstruction, silicone-induced disease.

ABSTRACT

Rare cases of adult Still is disease (AOSD) and autoimmune inflammatory syndrome induced by adjuvants (ASIA) have been reported in patients with silicone breast implants. We present a narrative literature review and synthesis of cases describing this association, with emphasis on the post-mastectomy context. We highlight the diagnostic, therapeutic and prognostic aspects, as well as implications for the follow-up of patients with breast reconstruction.


REFERENCES

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  2. Montalto M, Vastola M, Santoro L, La Regina M, Curigliano V, Manna R et al. Systemic inflammatory diseases and silicone breast prostheses: report of a case of adult Still disease and review of the literature. Am J Med Sci 2004; 327 (2): 102-104.

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  4. Shoenfeld Y, Agmon-Levin N. 'ASIA' - autoimmune/inflammatory syndrome induced by adjuvants. J Autoimmun 2011; 36 (1): 4-8.

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  7. Yamaguchi M, Ohta A, Tsunematsu T, Kasukawa R, Mizushima Y, Kashiwagi H et al. Preliminary criteria for classification of adult Still's disease. J Rheumatol 1992; 19 (3): 424-430.

  8. Maitani K, Kadowaki M, Yamagiwa Y, Yasuhara Y, Kozuki S, Otsuka Y et al. Three case reports of adult-onset still disease associated with breast implantation. Plast Reconstr Surg Glob Open 2024; 12 (5): e5844.

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  13. Caldarelli M, Rio P, Giambra V, Gasbarrini A, Gambassi G, Cianci R. ASIA syndrome: state-of-the-art and future perspectives. Vaccines 2024; 12 (10): 1183.

  14. Rodríguez-García FA, Servín-Rodríguez CE, Torres-Salazar QL. Autoimmune/inflammatory syndrome induced by adjuvants (ASIA): A case of systemic symptoms following breast implants and vaccinations. Int J Surg Case Rep. 2024 Oct 19;124:110497. doi: 10.1016/j.ijscr.2024.110497.

  15. Maijers MC, de Blok CJ, Niessen FB, van der Veldt AA, Ritt MJ, Winters HA et al. Women with silicone breast implants and unexplained systemic symptoms: a descriptive cohort study. Neth J Med 2013; 71 (10): 534-540.

  16. Spoor J, Mureau MA M, de Jong D, Tissier RL M et al. Autoimmune conditions and 'breast implant illness' in breast cancer patients with implant-based breast reconstructions. J Clin Oncol 2025; 43 (16 suppl): 12035.




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Cir Plast. 2025;35