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ISSN 1405-0625 (Print)

2025, Number 4

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Cir Plast 2025; 35 (4)

Skin that saves. Advances and challenges in the use of cadaveric grafts in burned patients

Romero-Argüello ÓA, Franco-Tormo MJ, Ascencio-Reyes JM, Miranda-Altamirano RA, González-Aboytes JE

Language: Spanish
References: 20
Page: 214-219
PDF size: 2488.96 Kb.


ABSTRACT

Burns are a global public health problem. Early excision of necrotic tissue within the first 24 to 48 hours after injury has significantly reduced mortality in severe burn cases. Autologous skin grafting remains the gold standard for definitive closure of full-thickness burns. However, in cases involving more than 30% of total body surface area, cadaveric skin grafting is an ideal alternative. One of the main challenges in this context is immunocompatibility; therefore, it is crucial to establish standardized and controlled management of allogeneic tissues to minimize the risk of rejection and optimize clinical efficacy. This article reviews the main indications, advantages, disadvantages and clinical outcomes, supported by scientific evidence concerning the use of cadaverous skin.


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