Samada SM, Valenzuela AK, Moret VS

Language: Spanish
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ABSTRACT

Introduction. Patients with liver transplant, due to the use of immunosuppressants and the comorbidities they present, may have a higher risk of presenting Covid-19, but its incidence and evolution are still topics of debate. Objective. To determine the behavior of Covid-19 in liver transplant patients. Methods. An observational, prospective and longitudinal study was carried out in 17 liver transplant patients from the Surgical Medical Research Center, who acquired Covid-19 between March 2020 and February 2022. Patients who tested positive for SARS-CoV-2 (through the nucleic acid test) were considered COVID-19 positive. The main variables of the study were: age, sex, clinical picture, comorbidities and mortality. Results. Of 69 patients with liver transplant, 17 (24.6%) had Covid-19, 9 (52.9%) were female and 58.8% were under 60 years of age. Regarding the clinical picture, 9 (52.9%) patients presented the uncomplicated form of the disease, of the comorbidities 94.1% had arterial hypertension, 23 % diabetes mellitus and 17 % renal dysfunction. Mortality from Covid-19 was 11.7 %, the two patients who died had arterial hypertension, previous renal dysfunction, and were older than 60 years. Conclusions. The behavior of Covid-19 in liver transplant patients could be similar to the general population, with great influence of age and comorbidities on mortality.