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2025, Number 4

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Med Crit 2025; 39 (4)

Body mass index and its impact on the clinical evolution of patients with severe pneumonia due to SARS-CoV-2: a post hoc analysis of a prospective cohort study

Rodríguez RK, Peniche MKG, Sánchez DJS, Reyes RJM, Calyeca SMV

Language: Spanish
References: 26
Page: 256-262
PDF size: 316.35 Kb.


ABSTRACT

Introduction: obesity is a multisystem disease, where body mass index (BMI) allows its diagnosis and classification. Severe pneumonia due to SARS-CoV-2 was a milestone in modern human history, leading to the increased use of invasive mechanical ventilation. Objective: to identify the association between BMI and outcome of patients with severe pneumonia due to SARS-CoV-2. Material and methods: this study is a post hoc analysis of a single-centre prospective cohort study of patients presenting diagnosis of severe pneumonia due to SARS-CoV-2 admitted to the Intensive Care Unit between May 1 and December 31, 2020. Results: a total of 115 patients were included; they were classified according to BMI < 24.9 kg/m2, 25-29.9 kg/m2, 30-34.9 kg/m2, 35-39.9 kg/m2, > 40 kg/m2, each group consisted of 9, 22, 47, 24 and 13 patients consecutively. Overall mortality was 53%; as a dichotomous variable, BMI > 33.7 kg/m2 presented OR 1.06 (95%CI 0.996-1.131) p = 0.065 for fatal outcome. Conclusion: BMI is not a risk factor for mortality; as an independent variable, it influences pulmonary parameters and impacts clinical evolution.


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