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Revista Mexicana de Trasplantes

ISSN 3122-3893 (Electronic)
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2026, Number 1

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Rev Mex Traspl 2026; 15 (1)

Monoclonal gammopathy as a differential diagnosis in tacrolimus toxicity

Hopf-Estandía K, Cano-Cervantes JH, Matías-Carmona M, Hernández-Hernández RC, Fernández-Vivar C
Full text How to cite this article 10.35366/122937

DOI

DOI: 10.35366/122937
URL: https://dx.doi.org/10.35366/122937

Language: Spanish
References: 1
Page: 45-46
PDF size: 182.18 Kb.


Key words:

acute graft dysfunction, tacrolimus toxicity, monoclonal gammopathy.

ABSTRACT

We present the clinical case of a kidney transplant recipient from a deceased donor, in whom protocol biopsies revealed intratubular casts as a possible finding related to acute tubular injury associated with tacrolimus use. However, due to the presence of these casts, monoclonal gammopathies must be ruled out as a potential cause of acute dysfunction.


REFERENCES

  1. Liptak P, Ivanyi B. Primer: histopathology of calcineurin-inhibitortoxicity in renal allografts. Nat Clin Pract Nephrol. 2006; 2 (7):398-404. doi: 10.1038/ncpneph0225.




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Rev Mex Traspl. 2026;15