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2023, Number 1

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Rev cubana med 2023; 62 (1)

Establishing Better Treatment for Hypothyroidism Patients

Gómez MJE, Infante AAL, Argüelles ZAC, Durán LDM, Turcios TSE
Full text How to cite this article

Language: Spanish
References: 12
Page: 1-6
PDF size: 405.96 Kb.


Key words:

hypothyroidism, treatment, levothyroxine, combination therapy.

ABSTRACT

Introduction: Hypothyroidism is an entity that is frequently seen at the endocrinologist´s. establishing the best treatment is a challenge, despite proper management and optimal hormonal control, sometimes patients continue with symptoms which affect their quality of life, therefore that treatment should be individualized, based on the best evidence.
Objective: To establish the best therapeutic options in hypothyroidism different forms of presentation.
Methods: A non-systematic bibliographic search was carried out in PubMed, Medline, LILACS, EMBASE, Redalyc databases and in the international guidelines. The inclusion criteria were publications in English and Spanish, in which the title, keywords or abstract include relevant information to the objective of the study, with a periodicity of no more than 5 years, except for the guidelines that the latest revisions were used. In the search, 30 articles were retrieved, 14 which were selected.
Conclusions: The therapeutic options were established in order to find better treatment for hypothyroid patients, which must be individualized and based on the best evidence, to achieve adequate control of the disease, to improve the quality of life and to avoid related complications.


REFERENCES

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  2. Jacome Roca A, Terapia de suplencia tiroidea: una historia del siglo XIX que aún genera noticias en el siglo XXI, Revista Colombiana de Endocrinología, Diabetes y Metabolismo. 2018 [acceso 14/03/2021];5(1)1. Disponible en: https://revistaendocrino.org2.

  3. Jonklaas J, Bianco A, Bauer A, Burman KD, Coppola AR, Celi FS, et al. Guidelines for the Treatment of Hypothyroidism. American Thyroid Association. 2014;24(12):1670-1751. DOI: http://doi.org/10.1089/thy.2014.00283.

  4. Bruton LL, Chabner BA, Knollmann BC. Tiroides y fármacos antitiroideos. En: Goodman & Gilman: Las bases farmacológicas de la terapéutica. 12 ed. México: Industria Editorial Mexicana. 2012. Disponible en: https://accessmedicina.mhmedical.com4.

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  9. Zijlstra LE, Jukema W, Westendorp R, Du Puy R, Poortvliet R, Kearney PM, et al. Levothyroxine Treatment and Cardiovascular Outcomes in Older People With Subclinical Hypothyroidism: Pooled Individual Results of Two Randomised Controlled Trials. Front. Endocrinol (Lausanne). 2012;12:674841. DOI: http://doi.org/10.3389/fendo.2021.6748419.

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C?MO CITAR (Vancouver)

Rev cubana med. 2023;62