2025, Number 4
Neonatal sepsis caused by Raoultella planticola: report of eight cases in a Mexican perinatal hospital
Language: Spanish
References: 17
Page: 212-218
PDF size: 243.25 Kb.
ABSTRACT
Background. In 2020, four cases of neonatal infection with Raoultella planticola were reported in China. This agent is recognized for its importance in generating antimicrobial resistance, particularly to meropenem.Case presentation. In 2023, eight (4%) of 197 neonates with sepsis were caused by R. planticola. Antimicrobial resistance reported for R. planticola was reported to cefepime and amikacin in case 1, to ampicillin sulbactam and ceftriaxone in case 5, and to cefoxitin in case 8. The remaining cases did not present antimicrobial resistance. In our series, four of the eight reported patients (50%) died; three had major malformations (37.7%) and seven were premature (87.5%), with an average gestational age of 32.1 weeks.
Conclusions. The common denominator of the literature highlights the recommendation that once R. planticola is identified in the hospital unit, it should be considered a microorganism with potential risk, due to its high capacity to develop resistance to carbapenems.
REFERENCES
Drancourt, M., Bollet, C., Carta, A. y Rousselier, P.,“Phylogenetic analyses of Klebsiella species delineateKlebsiella and Raoultella gen. Nov., with description ofRaoultella ornithinolytica comb. nov., Raoultella terrigenacomb. nov. and Raoultella planticola comb. nov.”,Int J Syst Evol Microbiol, 2001, 51 (Pt 3): 925-932. doi:10.1099/00207713-51-3-925.
Walckenaer, E., Poirel, L., Leflon-Guibout, V., Nordmann,P. y Nicolas-Chanoine, M.H., “Genetic and biochemicalcharacterization of the chromosomal class a beta-lactamasesof Raoultella (formerly Klebsiella) planticola andRaoultella ornithinolytica”, Antimicrob Agents Chemother,2004, 48 (1): 305-312. doi: 10.1128/AAC.48.1.305-312.2004.
Ramos Pinheiro, F, Rozza-de-Menezes, R.E., Blum,M.C., Freire Alves Pereira, R., Abel Rocha J., GuedesPinto, M.C.F., Penna, B.A., Riley, L.W. y Aguiar-Alves,F., “Evaluation of changes in antimicrobial susceptibilityin bacteria infecting children and their mothers inpediatric, neonatal-intensive care unit, and gynecology/obstetrics wards of a quaternary referral hospital duringthe covid-19 pandemic”, Front Microbiol, 2023, 14:1096223. doi: 10.3389/fmicb.2023.1096223.
Yang, C., Xu, Q., Xie, M., Tang, Y., Hu, Q., Heng, H., Yang,X., Liu, X., Chan, E.W., Yang, G. y Chen, S., “Enhancingresistance, but not virulence attributed to the highmortality caused by carbapenem-resistant Klebsiellapneumoniae”, Microbiol Res, 2024, 285: 127769. doi: 10.1016/j.micres.2024.127769.
Kiiru, S., Maina, J., Mwaniki, J.N., Songoro, E. y Kariuki,S., “Enteric bacterial agents associated with diarrheaand their antimicrobial sensitivity profiles in childrenunder 5 years from mukuru informal settlement, Nairobi,Kenya”, bmc Infect Dis, 2024, 24 (1): 237. doi.org/10.1186/s12879-024-09114-5.
Cissoko, Y., Maiga, A., Dabitao, D., Dicko, M.S., Koné,D., Konaté, I., Dembele, J.P., Sidibe, A.F., Maiga, I.I. yDao, S., “Raoultella planticola and urinary tract infection:the first laboratory-confirmed case in an hiv-infected patientin Mali”, J Infect Dev Ctries, 2022, 1 (5): 909-912.doi: 10.3855/jidc.15688.