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2026, Number 4

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Acta Med 2026; 24 (4)

Brown tumors in the context of chronic kidney disease and double primary hyperparathyroidism detected by SPECT/CT with [99mTc]Sestamibi

Bello MA, Córdova GDE, Schalch PLJM, Serna MJA, Rodríguez UGE, Sánchez GLC
Full text How to cite this article 10.35366/123516

DOI

DOI: 10.35366/123516
URL: https://dx.doi.org/10.35366/123516

Language: Spanish
References: 5
Page: 460-463
PDF size: 1116.67 Kb.


Key words:

brown tumors, parathyroid adenoma, hyperparathyroidism, SPECT/CT, parathyroid scintigraphy.

ABSTRACT

We describe one of the rare causes of hyperparathyroidism in a 29-year-old male patient with chronic kidney disease since he was 8-years-old with no primary cause. He had received two transplants, resulting in dysfunction of both grafts, and was subsequently treated with hemodialysis. During follow-up, he responded poorly to conventional measures to lower serum calcium, so he consulted an endocrinologist, who ordered parathyroid scintigraphy and Single-Photon Emission Computed Tomography/Computed Tomography (SPECT/CT), revealing two parathyroid adenomas and multiple brown tumors.


REFERENCES

  1. Jacquet-Francillon N, Prevot N. Brown tumors in nuclear medicine:a systematic review. Ann Nucl Med. 2023; 37 (5): 255-270.

  2. Krishna Mohan VS, Narayan ML, Mukka A, Bachimanchi B, ChowhanAK, Devi BV et al. Atypical parathyroid adenoma with multiple browntumors as initial presentation: a rare entity. Indian J Nucl Med. 2017; 32 (2): 133-136.

  3. Hoang JK, Sung WK, Bahl M, Phillips CD. How to perform parathyroid 4D CT: tips and traps for technique and interpretation. Radiology.2014; 270 (1): 15-24.

  4. Greenspan BS, Dillehay G, Intenzo C, Lavely WC, O’Doherty M,Palestro CJ et al. SNM practice guideline for parathyroid scintigraphy4.0. J Nucl Med Technol. 2012; 40 (2): 111-118.

  5. Nael K, Hur J, Bauer A, Khan R, Sepahdari A, Inampudi R et al.Dynamic 4D MRI for characterization of parathyroid adenomas:multiparametric analysis. AJNR Am J Neuroradiol. 2015; 36 (11):2147-2152.




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Acta Med. 2026;24