Chávez-Hernández, Kristna-Pamela; Montoya-Quintero, María-de-Lourdes; Rojo-Rodríguez, Bárbara-Isamara; García-Ferreiro, Víctor-Joaquín; Rodríguez-Gutiérrez, Jesús-Sebastián

Language: Spanish
References: 13
Page: 194-197
PDF size: 238.58 Kb.

ABSTRACT

Alopecia areata is a non-scarring autoimmune disorder characterized by hair loss resulting from the collapse of immune privilege in hair follicles during the anagen phase. Its estimated prevalence ranges from 0.7% to 3.8%. While it can occur at any stage of life, it most frequently affects individuals between 15 and 45 years of age. We report the case of a 13-year-old adolescent presenting with scalp alopecia along with involvement of the eyebrows, eyelashes, axillae, and pubic region. A diagnosis of alopecia universalis was established. Treatment with methotrexate and corticosteroids was initiated, achieving nearly complete hair regrowth across all affected areas.

REFERENCES

1. Rudnicka L, Arenbergerova M, Grimalt R, et al. European expertconsensus statement on the systemic treatment of alopeciaareata. Journal of the European Academy of Dermatology andVenereology 2024;38(4):687–694.

2. Gómez-Quispe H, Muñoz Moreno-Arrones O, Hermosa-Gelbard,et al. [Translated article] Trichoscopy in Alopecia Areata. ActasDermosifiliogr 2023;114(1):T25–T32.

3. Mesinkovska NA, King BA, Vañó-Galván S, et al. VisualizingSeverity of Alopecia Tool (SALT) scores in the clinical settingusing patient images from a clinical trial. 2023.

4. Joly P, Lafon A, Houivet E, et al. Efficacy of Methotrexate Alonevs Methotrexate Plus Low-Dose Prednisone in Patients WithAlopecia Areata Totalis or Universalis: A 2-Step Double-BlindRandomized Clinical Trial. JAMA Dermatol 2023;159(4):403–410.

5. Mokhtari F, Ganjei Z, Yazdanpanah M, et al. Inverse correlationbetween vitamin D and CRP levels in alopecia areata: A pilotstudy. J Cosmet Dermatol 2023;22(11):3176–3180.

6. Dhurat R, Sharma R. A Practical Approach to the Treatment ofAlopecia Areata. Indian Dermatol Online J 2022;13(6):725–728.

7. Albela H, Begum S, Wee AL, et al. Efficacy and Tolerability ofMethotrexate in the Treatment of Severe Paediatric AlopeciaAreata. Skin Appendage Disord 2022;8(3):206–210.

8. Vera Ramírez V, Shalom K, Mendoza A. Alopecia areata universalistreated with oral pulse of dexamethasone. A case report. 2022.

9. Thi Van AT, Lan AT, Anh MH, et al. Efficacy and Safety ofMethotrexate in Combination with Mini Pulse Doses of Methylprednisolonein Severe Alopecia Areata. The VietnameseExperience. Open Access Maced J Med Sci 2019;7(2):200–203.

10. Hammerschmidt M, Brenner FM. Efficacy and safetyof methotrexate in alopecia areata. An Bras Dermatol2014;89(5):729–734.

11. Ait Ourhroui M, Hassam B, Khoudri I. [Treatment of alopeciaareata with prednisone in a once-monthly oral pulse]. AnnDermatol Venereol 2010;137(8–9):514–518.

12. Chartaux E, Joly P. Évaluation à long terme de l’efficacité duméthotrexate seul ou associé à de faibles doses de corticoïdesdans le traitement des pelades décalvantes totales. AnnDermatol Venereol 2010;137(8–9):507–513.

13. Joly P. The use of methotrexate alone or in combination withlow doses of oral corticosteroids in the treatment of alopeciatotalis or universalis. J Am Acad Dermatol 2006;55(4):632–636.