medigraphic.com
SPANISH

MediSan

ISSN 1029-3019 (Electronic)
  • Contents
  • View Archive
  • Information
    • General Information        
    • Directory
  • Publish
    • Instructions for authors        
  • medigraphic.com
    • Home
    • Journals index            
    • Register / Login
  • Mi perfil

2023, Number 02

<< Back Next >>

MediSan 2023; 27 (02)

Differences according to sex in patients admitted to intensive care units

González AC, Cabrera LJO, Vázquez BYE, Arias OA
Full text How to cite this article

Language: Spanish
References: 20
Page:
PDF size: 520.70 Kb.


Key words:

sex, risk factors, intensive care units, critical patient, secondary health care.

ABSTRACT

Introduction: Nowadays disparities as for sex in patients with serious diseases can be found, which has not been explained in the clinical-epidemiological studies carried out until the moment.
Objective: To identify the differences according to sex in patients admitted to intensive care units.
Methods: An observational and prospective study of 187 patients admitted to the Intensive Care Units of Carlos Manuel de Céspedes Provincial General Hospital was carried out in Granma that included the months of November and December, 2018-2020. Among the analyzed variables we can mention: age, sex, origin, diagnosis at admission, state when discharged from the unit, hospital stay, syndrome of systemic inflammatory response, stage of the sepsis, risk factors, community acquired infections and required treatment.
Results: In the investigation most of the patients corresponded to female sex (60.9 %) and the mean age was 31.6 and 49.6 years in women and men, respectively (p=0.000). Also, significant differences existed as for the origin (p=0.012) and the initial diagnoses (p=0.018); while the average of the APACHE II was 7.2 in women and 11.6 in men (p=0.000) and the Sequential Organ Failure Assessment Score had a mean of 0.7 and 2.0, in that same order (p=0.000).
Conclusions: The patients of male sex presented average age, diagnosis, origin, seriousness and dysfunction of organs significantly different to those of female sex. Although disparities were not appreciated as for risk factors and infections associated with the community, the frequency of men that require treatment was significantly higher.


REFERENCES

  1. Hollinger A, Gayat E, Féliot E, Paugam Burtz C, Fournier MC, Duranteau J, et al. Gender and survival of critically ill patients: results from the FROG-ICU study. Ann Intensive Care. 2019 [citado 31/01/2023];9(43):1-8. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441070/pdf/13613_2019_Article_514.pdf

  2. Sunden Cullberg J, Nilsson A, Inghammar M. Sex-based differences in ED management of critically ill patients with sepsis: a nationwide cohort study. Intensive Care Med. 2020 [citado 31/01/2023];46:727-36. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103003/pdf/134_2019_Article_5910.pdf

  3. Modra L, Higgins A, Vithanage R, Abeygunawardana V, Bailey M, Bellomo R. Sex differences in illness severity and mortality among adult intensive care patients: A systematic review and meta-analysis. J Critical Care. 2021 [citado 31/01/2023];65:116-23. Disponible en: https://reader.elsevier.com/reader/sd/pii/S0883944121001064?token=7495DD09B944EAFE9BFACDEB1ED178A3715EADB7A5251A015B23F9B461CB6E83DC72593AFADBBA5E6357E03B4BF74069&originRegion=eu-west-1&originCreation=202304103164642

  4. Hessey E, Montgomery C, Zuege DJ, Rolfson D, Stelfox HT, Fiest KM, et al. Sex-specific prevalence and outcomes of frailty in critically ill patients. J Intensive Care. 2020 [citado 31/01/2023];8(75). Disponible en: https://jintensivecare.biomedcentral.com/articles/10.1186/s40560-020-00494-9

  5. 5.Kuehnemund L, Koeppe J, Feld J, Wiederhold A, Illner J, Makowski L, et al. Gender differences in acute myocardial infarction-A nationwide German real-life analysis from 2014 to 2017. Clin Cardiol. 2021 [citado 31/01/2023];44:890-98. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8259152/pdf/CLC-44-890.pdf

  6. Arslani K, Tontsch J, Todorov A, Gysi B, Kaufmann M, Kaufmann F, et al. Temporal trends in mortality and provision of intensive care in younger women and men with acute myocardial infarction or stroke. Crit Care. 2023 [citado 31/01/2023];27(14):1-12. Disponible en: https://ccforum.biomedcentral.com/counter/pdf/10.1186/s13054-022-04299-0.pdf

  7. Cai YK, Liu Z, Jia CG, Zhao JW, Chai SS, Li Z, Xu CS, et al. Comparison of Sex Differences in Outcomes of Patients With Aneurysmal Subarachnoid Hemorrhage: A Single-Center Retrospective Study. Front Neurol. 2022 [citado 31/01/2023];13(853513):1-8. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9103686/pdf/fneur-13-853513.pdf

  8. Kondo Y, Miyazato A, Okamoto K, Tanaka H. Impact of Sex Differences on Mortality in Patients With Sepsis After Trauma: A Nationwide Cohort Study. Front Immunol. 2021 [citado 31/01/2023];12(678156):1-6. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8276106/pdf/fimmu-12-678156.pdf

  9. Larsson E, Lindström AC, Eriksson M, Oldner A. Impact of gender on post-traumatic intensive care and outcomes. Scand J Trauma Resusc Emerg Med. 2019 [citado 31/01/2023];27(115):1-7. Disponible en: https://sjtrem.biomedcentral.com/counter/pdf/10.1186/s13049-019-0693-4.pdf

  10. Navarrete Arauz RM, Tercero Martínez WM, Aguayo Moscoso SX, Vélez Páez JL, Vélez Páez JW, Vélez Páez PA, et al. Hormonas sexuales en la enfermedad crítica. Cambios Rev Méd. 2019 [citado 31/01/2023];18(2):72-9. Disponible en: https://docs.bvsalud.org/biblioref/2020/06/1099677/art_11_cambios_2019_7v_final.pdf

  11. Bone RC, Balk RA, Cerra FB, Dellinger RP, Fein AM, Knaus WA, et al. Definitions for sepsis and organ failure and guidelines for the use innovative therapies in sepsis. The ACCP/SCCM Consensus Conference. 1992;101(6):1644-55.

  12. Singer M, Deutschman CS, Seymour CW, Shankar-Hari M, Annane D, Bauer M, et al. The Third International Consensus Definition for Sepsis and Septic Shock (Sepsis-3). JAMA. 2016 [citado 31/01/2023];315(8):801-10. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4968574/pdf/1nihms794087.pdf

  13. Knaus WA, Draper EA, Wagner DP, Zimmerman JE. APACHE II: a severity of disease classification system. Crit Care Med. 1985 [citado 31/01/2023];13(10):818-29. Disponible en: https://www.researchgate.net/profile/William-Knaus-2/publication/19234189_APACHE_II_a_severity_of_disease_classification_system/links/5e35b24e458515072d76d9e5/APACHE-II-a-severity-of-disease-classification-system.pdf?origin=publication_detail

  14. Vincent JL, Ferreira F, Moreno R. Scoring systems for assessing organ dysfunction and survival. Crit Care Clin. 2000 [citado 31/01/2023];16(2):353-66. Disponible en: https://www.researchgate.net/profile/Flavio-Ferreira-8/publication/12548673_Scoring_systems_for_assessing_organ_dysfunction_and_survival/links/5b4c7935aca272c609477b76/Scoring-systems-for-assessing-organ-dysfunction-and-survival.pdf

  15. Olaechea PM, Álvarez Lerma F, Palomar M, Gimeno R, Gracia MP, Mas N, et al. Characteristics and outcomes of patients admitted to Spanish ICU: A prospective observational study from the ENVIN-HELICS registry (2006-2011). Med Intensiva. 2016 [citado 31/01/2023];40(4):216-29. Disponible en: https://www.medintensiva.org/index.php?p=revista&tipo=pdf-simple&pii=S2173572716300121

  16. National Healthcare Safety Network. CDC/NHSN Surveillance Definitions for Specific Types of Infections. Atlanta: CDC; 2023 [citado 31/01/2023]. Disponible en: https://www.cdc.gov/nhsn/pdfs/pscmanual/17pscnosinfdef_current.pdf

  17. Abdo Cuza A, Castellanos Gutiérrez R. Incidencia de infecciones relacionadas con el cuidado sanitario en unidades de cuidados intensivos en Cuba: ańo 2015 e informe de tendencias del primer quinquenio. Invest Medicoquir. 2017 [citado 31/01/2023];9(1):67-95. Disponible en: https://revcimeq.sld.cu/index.php/imq/article/download/374/462

  18. Zettersten E, Jäderling G, Larsson E, Bell M. The impact of patient sex on intensive care unit admission: a blinded randomized survey. Scientific Report. 2019 [citado 31/01/2023];9(14222):1-4 Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6775127/pdf/41598_2019_Article_50836.pdf

  19. Vezzani A, Manca C, Ermio C. Gender disparities in the Intensive Care Unit. Ital J Gender Specific Med. 2016 [citado 31/01/2023];2(1):22-7. Disponible en: https://www.gendermedjournal.it/r.php?V=2288&a=24608&l=326748&f=allegati/02288_2016_01/fulltext/22-27_Vezzani.pdf

  20. Nouri Pasovsky PA, Nachtigall I, Krannich A, Spies C, Tafelski S. Evaluation of sex-associated differences in validity of the SOFA score in ICU patients. Ital J Gender-Specific Med. 2021 [citado 31/01/2023];7(1):7-14. Disponible en: https://www.gendermedjournal.it/r.php?v=3528&a=35161&l=343270&f=allegati/03528_2021_01/fulltext/07-14_Original%20article_Pasovsky.pdf




CC BY-NC-ND

2020     |     www.medigraphic.com

Mi perfil

C?MO CITAR (Vancouver)

MediSan. 2023;27