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Instituto Nacional de Salud Pública

2026, Number 4

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salud publica mex 2026; 68 (4)

Measurement of opioid misuse in the general Mexican population: Encodat 2025

Sánchez-Pájaro A, Reyes-García A, Rivera-Aguirre A, Rivero-Treviño MJ, Cruz SL, López-Brambila MÁ, Pech-Puebla D, Cerdá M

Language: English
References: 24
Page: 342-347
PDF size: 234.00 Kb.


ABSTRACT

Objective. To examine the prevalence of categorical self-reported opioid misuse and compare it to a post hoc corrected indicator in the general Mexican population. Materials and methods. We used data from the 2025 Encuesta Nacional de Consumo de Drogas, Alcohol y Tabaco. We constructed indicators from self-reported categorical heroin/ fentanyl use, prescription opioids misuse and opioid misuse and post hoc corrected versions based on the review of openended follow up questions by two experts. We estimated the prevalence from categorical self-report responses and compared it with the post hoc corrected indicators. Results. The prevalence of self-reported prescription opioid misuse was 1 948.3 per 100 000 people, which decreased to 1 242.4 after correction. Self-reported heroin or fentanyl use was 370.7 per 100 000 people, with a corrected prevalence of 326.2. Self-reported opioid misuse had a prevalence of 2 229.6 per 100 000 people, which decreased to 1 482.3 after correction. Conclusion. Misclassification was more frequent for prescription opioid misuse than for illicit opioid use. Simple categorical questions performed well for measuring illicit opioid use, but they moderately overestimated prescription and overall opioid misuse.


REFERENCES

  1. Substance Abuse and Mental Health Services Administration. Keysubstance use and mental health indicators in the United States: Resultsfrom the 2024 National Survey on Drug Use and Health. Center forBehavioral Health Statistics and Quality, Substance Abuse and MentalHealth Services Administration; 2025. Report HHS Publication No. PEP25-07-007, NSDUH Series H-60 [cited April 2, 2026]. Available from: https://www.samhsa.gov/data/sites/default/files/reports/rpt56287/2024-nsduhannual-national-report.pdf

  2. Fleiz C, Arredondo J, Chavez A, Pacheco L, Segovia LA, Villatoro JA, et al.Fentanyl is used in Mexico’s northern border: current challenges for drughealth policies. Addiction. 2020;115(4):778-81. https://doi.org/10.1111/add.14934

  3. Bautista CF, Medina-Mora ME, Cruz SL, López-Brambila MA, Miranda-Soto V, Chávez D, et al. Fentanyl, amphetamine-type stimulants, heroin, andxylazine in drug residues in two Northern border Mexican cities. HarmReduct J. 2025;23(1):12. https://doi.org/10.1186/s12954-025-01355-0

  4. Fleiz C, Villatoro J, Dominguez M, Bustos M, Medina-Mora ME. Opioidcrisis along Mexico’s Northern border: treatment needs Mexicanopioid crisis. Arch Med Res. 2019;50(8):527-34. https://doi.org/10.1016/j.arcmed.2019.12.013

  5. Henson RM, Mullachery PH, Sánchez-Pájaro A, Cruz-Cruz C, Bilal U,Langellier B, et al. Spatial heterogeneity in fatal overdose rate trendsin Mexican cities: 2005–2021. Am J Public Health. 2024;114(7):705-13.https://doi.org/10.2105/AJPH.2024.307650

  6. Bejarano-Romero R, Arredondo-Sánchez-Lira J, Slim-Pasaran S, Chávez-Rivera A, Angulo-Corral L, Salimian A, et al. Implementing a decentralizedopioid overdose prevention strategy in Mexico, a pending public policyissue. Lancet Reg Health Am. 2023;23:100535. https://doi.org/10.1016/j.lana.2023.100535

  7. Shield KD, Ialomiteanu A, Fischer B, Rehm J. Assessing the prevalenceof non-medical prescription opioid use in the Canadian general adultpopulation: evidence of large variation depending on survey questionsused. BMC Psychiatry. 2013;13:6. https://doi.org/10.1186/1471-244X-13-6

  8. Reimers A, Odin P, Ljung H. Drug-induced cognitive impairment. DrugSaf. 2025;48(4):339-61. https://doi.org/10.1007/s40264-024-01506-5

  9. Latkin CA, Edwards C, Davey-Rothwell MA, Tobin KE. The relationshipbetween social desirability bias and self-reports of health, substance use,and social network factors among urban substance users in Baltimore,Maryland. Addict Behav. 2017;73:133-6. https://doi.org/10.1016/j.addbeh.2017.05.005

  10. Observatorio Argentino de Drogas, Instituto Nacional de Estadísticay Censos, Secretaría de Políticas Integrales sobre Drogas de la NaciónArgentina. Encuesta Nacional de Consumos y Prácticas de Cuidado.Cuestionario 2022. Buenos Aires: INDEC, 2023 [cited February 27, 2026].Available from: https://www.argentina.gob.ar/sites/default/files/2023/08/cuestionario_encuesta_nacional_de_consumos_y_practicas_de_cuidado_.pdf

  11. Observatorio Chileno de Drogas, Servicio Nacional para la Prevencióny Rehabilitación del Consumo de Drogas y Alcohol. Cuestionario:décimo sexto estudio nacional de drogas en población general de chile.Santiago: SENDA, 2024 [cited February 27, 2026]. Available from: https://www.senda.gob.cl/base-de-datos-y-cuestionario-encuesta-nacional-depoblacion-general-2024/

  12. Substance Abuse and Mental Health Services Administration. 2024National Survey on Drug Use and Health (NSDUH): Final In-PersonSpecifications for Programming (English Version). Rockville: SAMHSA, 2023[cited February 27, 2026]. Available from: https://www.samhsa.gov/data/sites/default/files/reports/rpt44494/2024-nsduh-mrb-cai-specs.pdf

  13. Groves RM. Survey errors and survey costs. Wiley, 1989 [citedFebruary 27, 2026]. Available from: https://onlinelibrary.wiley.com/doi/book/10.1002/0471725277?msockid=0160d0a50f93683d2411c1d40ec469b3

  14. Comisión Nacional de Salud Mental y Adicciones, Instituto Nacionalde Psiquiatría Ramón de la Fuente Muñiz, Instituto Nacional de SaludPública. Encuesta Nacional de Consumo de Drogas, Alcohol y TabacoEncodat 2025. México: Conasama, 2025 [cited January 22, 2025]. Availablefrom: https://www.gob.mx/cms/uploads/attachment/file/1044513/ENCODAT_-_COMPLETO.pdf

  15. Palamar JJ. Barriers to accurately assessing prescription opioid misuseon surveys. Am J Drug Alcohol Abuse. 2019;45(2):117-23. https://doi.org/10.1080/00952990.2018.1521826

  16. Comisión Nacional De Salud Mental y Adicciones, Instituto Nacionalde Psiquiatría Ramón de la Fuente Muñiz, Instituto Nacional de SaludPública. Metodología de la Encuesta Nacional de Consumo de Drogas,Alcohol y Tabaco 2025. Salud Publica Mex. 2025;67(5):515-22. https://doi.org/10.21149/17295

  17. Fleiz-Bautista C, Medina-Mora ME. Fentanyl and xylazine on theNorthern Border of Mexico: A New Challenge for Drug Health Policy.Salud Ment. 2024;47(5):205-6. https://doi.org/10.17711/SM.0185-3325.2024.030

  18. Sánchez-Pájaro A. Supplementary material “Measurement of opioidmisuse in the general Mexican population: Encodat 2025.” NYU Langone,2026. https://doi.org/10.6084/m9.figshare.32320314

  19. León PJ, Altermatt FR, Vega EA, Elgueta MF, Léniz J. Opioid use in LatinAmerica: Chronicle of a death foretold? J Glob Health. 2024;14:03040.https://doi.org/10.7189/jogh.14.03040

  20. OECD, The World Bank. Health at a Glance: Latin America andthe Caribbean 2023. OECD Publishing, 2023 [cited May 6, 2026].Available from: https://www.oecd.org/en/publications/health-at-aglance-latin-america-and-the-caribbean-2023_532b0e2d-en.htmldoi:10.1787/532b0e2d-en

  21. Ramírez-Bontá F, Vásquez-Vílchez R, Cabrera-Alva M, Otazú-AlfaroS, Almeida-Huanca G, Ambrosio-Melgarejo J, et al. Mental health dataavailable in representative surveys conducted in Latin America and theCaribbean countries: a scoping review. BMJ Open. 2023;13(10):e069861.https://doi.org/10.1136/bmjopen-2022-069861

  22. Kroutil LA, Vorburger M, Aldworth J, Colliver JD. Estimated drug usebased on direct questioning and open-ended questions: responses in the2006 National Survey on Drug Use and Health. Int J Methods PsychiatrRes. 2010;19(2):74-87. https://doi.org/10.1002/mpr.302

  23. Palamar JJ, Shearston JA, Cleland CM. Discordant reporting ofnonmedical opioid use in a nationally representative sample of US highschool seniors. Am J Drug Alcohol Abuse. 2016;42(5):530-8. https://doi.org/10.1080/00952990.2016.1178269

  24. Observatorio Interamericano Sobre Drogas, Comisión Interamericanapara el Control del Abuso de Drogas. Protocolo para la Encuesta enPoblación General. Washington DC: OEA/CICAD, 2021 [cited January 22,2025]. Available from: https://www.oas.org/ext/DesktopModules/MVC/OASDnnModules/Views/Item/Download.aspx?type=1&id=945&lang=2




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