Tiribelli C

Language: English
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In whom, how and how often is surveillance for hepatocellular carcinoma cost-effective, by AL Ruelas-Villavicencio et al.

Hepatocellular carcinoma (HCC) is an increasingly frequent diagnosis, particularly after the introduction of US routine screening in patients with chronic liver disease. Data collected in series originating from different regions of the world showed a yearly incidence rate of about 3-5% in cirrhotic patients pointing to the need of a cost-effective screening protocol for early diagnosis and more effective treatment. This paper addresses this still controversial issue and namely which is the best time frame to perform screening protocols in subjects with chronic liver disease at risk for the development of HCC.