Tiribelli C

Language: English
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Page: 243
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Phytotherapeutic compound YHK by F. Marotta et al.

This study reports on the effect of an herbal compound (named YHK) on an animal model of hepatocellular carcinoma. Rats were given diethylnitrosamine with or without the herbal mixture, followed for 15 weeks, and the appearance of liver tumor compared in the two groups. Surprisingly, YHK administration was associated with both a reduction in the number of cells positive for glutathione-S-transferase, a marker of preneoplastic cell lesion, and in the number and volume of neoplastic lesions in the liver. This is potentially good news since we need alternative effective treatments for this increasingly frequent cancer but needs to be regarded with caution when we translate the results to humans.