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Acta Ortopédica Mexicana

ISSN 2992-8036 (Electronic)
ISSN 2306-4102 (Print)
Órgano Oficial del Colegio Mexicano de Ortopedia y Traumatología
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2007, Number 5

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Acta Ortop Mex 2007; 21 (5)

Utility of platelet-rich plasma and growth factors bone in the bone defects. Regional Hospital Lic. Adolfo López Mateos, ISSSTE

Mendieta ATR, Alvarado SJC, Negrete CJ
Full text How to cite this article

Language: Spanish
References: 18
Page: 256-260
PDF size: 164.89 Kb.


Key words:

arthroplasty, platelet-rich plasma, bone development, growth factors, bone regeneration.

ABSTRACT

Introduction: The platelet-rich plasma is a concentrated of platelets with the presence of growth factors and proteins that serve as osteoconducer matrix for bone formation. We present the results obtained with the use of platelet-rich plasma and a hydroxyapatite and bovine collagen graft in the management of bone defects. Material and methods: We studied eight patients with bone defects, treated surgically in whom platelet rich plasma and a hydroxyapatite and bovine collagen graft was used, with clinical and radiographic follow-up at 2, 4, 6, 10 and 18 weeks after surgery. Results: Starting on week 7 since surgery, evidence of osteointegration and bone callus formation, during the weeks 10 and 14 most cases showed bone consolidation. A case without consolidation through week 18. Discussion: The immediate response of the body tissue damaged is the accumulation of a large number of activated platelets, which release their granules and growth factors that promote the regeneration of tissues. It is possible to obtain platelet-rich plasma and accelerating the process of bone regeneration. Our study shows beneficial results with the use of platelet-rich plasma.


REFERENCES

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Acta Ortop Mex. 2007 Sep-Oct;21