medigraphic.com
Academia Mexicana de Neurología, A.C.

2006, Number 2

<< Back Next >>

Rev Mex Neuroci 2006; 7 (2)

The unprecise destiny of a neuronal lineage, Cajal-Rezius cells

Flores-Cruz MG, Escobar A

Language: Spanish
References: 10
Page: 147-149
PDF size: 0. Kb.


ABSTRACT

Neuronal proliferation during central nervous system (CNS) development is a phenomenon comparable to programmed neu-ronal death. Once CNS development ends, several neuronal lineages die or change their morphology, as it occurs to Cajal-Retzius cells whose proliferation peak takes place during embryonic period. At ontogeny, CRc synthesize and release reelin, a stop-signal protein for the migrating neurons to the cortical layers, although at the end of neuronal migration the majority of CRc disappear from layer I at neocortex. The fate of Cajal-Retzius cells and the possible mechanisms related to the “vanishing” of these neurons has been subject only of recent research.


REFERENCES

  1. Roth KA. Programmed cell death. In: Rao MS, Jacobson M (eds). Developmental Neurobiology, New York: Kluver Academic/Plenum Publishers; 2005, p. 317-28.

  2. Mienville JM, Pesold C. Low resting potentials and postnatal upregulation of NMDA receptors may cause Cajal-Retzius cell death. J Neurosci 1999; 19: 1636-46.

  3. Douglas R, Markram H, Martin K. Neocortex. In: Sheperd GM ed. The Synaptic Organization of the Brain. New York: Oxford University Press; 2004, p. 499-558.

  4. Polleux F, Anton ES. Neuronal migration in the developing brain. In: Rao MS, Jacobson M (eds). Developmental Neurobiology. New York: Kluver Academic/ Plenum Publishers; 2005, p. 223-40.

  5. Soriano E, del Río JA. The cells of Cajal-Retzius: Still a mystery one century after. Neuron 2005; 46: 389-94.

  6. Marín-Padilla M. Cajal-Retzius cells and the development of the neocortex. TINS 1998; 21: 64-71.

  7. Mienville JM, Barker JL. Potassium current expression during prenatal corticogenesis in the rat. Neurosci 1997; 81: 163-72.

  8. Zhou FM, Hablitz JJ. Postnatal development of membrane properties of layer I neurons in rat neocortex. J Neurosci 1996; 16: 1131-9.

  9. Mieville JM. Persistent depolarizing action of GABA in rat Cajal-Retzius cells. J Physiol 1998; 512(3): 809-17.

  10. Ringstedt T, Linnarson S, Wagner J, Lendalh U, Kokaia Z, Arenas E, Ernfors P, Ibáñez CF. BDNF regulates reelin expression and Cajal-Retzius cell development in the cerebral cortex. Neuron 1998; 21: 305-15.




2020     |     www.medigraphic.com