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1998, Number 4

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Med Crit 1998; 12 (4)

¿Are low-dose dopamine and low-dose dobutamine useful in the management of renal dysfunction of the ICU patient?

Cruz ME, Hernández-Rojas ME
Full text How to cite this article

Language: Spanish
References: 6
Page: 127-129
PDF size: 46.72 Kb.


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Intrinsic acute renal failure due to acute tubular necrosis (ATN) is associated with a varying degree of oliguria, rising serum creatinine levels, decrease of renal blood flow (RBF), large drop in glomerular filtration rate (GFR) and tubular disorders. Severe acute renal failure is a major component of the multiorgan failure syndrome and is associated with a mortality rate of 50% in critically ill patients, despite renal replacement therapies. Since renal hypoxia can play an important role in its pathogenesis, management goals include strategies to optimize RBF.3 Low-dose dopamine (LDD) selectively dilates renal vessels, increasing RBF, GFR and sodium excretion;


REFERENCES

  1. Carcoana OV, Hines RL. Is renal dose dopamine protective or therapeutic? Yes. Crit Care Clin 1996; 12: 677-685.

  2. Cotre DBF, Saul W. Is renal dose dopamine protective or therapeutic? No. Crit Care Clin 1996; 12: 687-695.

  3. Parker S, Carlon GC, Isaacs M, Howland WS, Kahn RC. Dopamine administration in oliguria and oliguric renal failure. Crit Care Med 1981; 9: 630-632.

  4. Duke GJ, Briedis JH, Weavere RP. Renal support in critically ill patients: Low-dose dopamine or low-dose dobutamine? Crit Care Med 1994; 22: 1919-1925.

  5. Lara GBM, Rosas GA, Cervantes OP. Estudio comparativo con dosis bajas de dobutamina y dopamina en el manejo de la insuficiencia renal en el paciente crítico. Rev Asoc Mex Med Crit y Ter Int 1998; 12: 79-83.

  6. García NJJ, Molinar RF, Baltazar TJA, Cervantes MC, Cruz ME. Comparación de los efectos renales de la dobutamina y la dopamina en pacientes en estado crítico. Rev Asoc Mex Med Crit y Ter Int 1996; 10: 154-158.




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C?MO CITAR (Vancouver)

Med Crit. 1998;12