Romero GMB, Durán PMA, Alcántara VA, Hernández GM, Hopp GK, Rivas VS

Language: Spanish
References: 15
Page: 168-174
PDF size: 279.15 Kb.

ABSTRACT

The matured T lymphocytes neoplasms originate from posthymic cells and are considered for their study together with those derived from NK cell. They are not frequent in lymph nodes, the most common type is the non specific peripheral T cell (3.7%) followed by the anaplastic T/null large cells (2.4%). From a total of 463 cases of non Hodgkin lymphomas studied in a period of five years, 76 (16.4%) were of to T/NK type. Twenty four cases were in lymph node found (5.4%), 14 in females and 10 in men. The average age was 42.6 years. Histological 10 (41.6%) were non-specific T peripheral lymphocytes, 10 (41.6%) were T/Null anaplastic, 3 (12.5%) were to T angioimmunoblastic and one (4.1%) had morphology changes similar to the NK nasal type, but was negative to Cd 56 and had cytotoxic granules. The expression for different T cell markers was variable. The CD30 was constantly positive in anaplastic lymphoma but not so to ALK (anaplastic lymphoma kinase). The association with the Epstein-Barr virus was demonstrated in 14 of 21 cases (66.6%). The differential diagnosis has to be made with Hodgkin lymphoma. In this series the T cell lymphoma of lymph node is considered infrequent and there is a predominance in female, something not found in the literature. The average age was 42.6 year, which is below the reported in the word literature. The association with the Epstein-Barr virus was however, frequent. The main objectives of this report are to show the frequency, morphological types, differential diagnosis and association with the Epstein-Barr virus of the non Hodgkin T lymphoma of the lymph node, in a 5 years period.

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