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Anales de la Sociedad Mexicana de Oftalmología y Archivos de la Asociación Para Evitar la Ceguera en México

2006, Number 3

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Rev Mex Oftalmol 2006; 80 (3)

Brinzolamida tópica para el tratamiento de la coroidorretinopatía serosa central idiopática

Ontiveros-Orozco I, García-Franco R, Levine-Berevichez A, López-Star EM, Rojas-Juárez S, Celis-Suazo B, Rentería-García H

Language: Spanish
References: 19
Page: 132-137
PDF size: 77.18 Kb.


ABSTRACT

Purpose: To determine the efficacy and safety of topical brinzolamide in the treatment of idiopathic central serous chorioretinopathy (ICSC).
Patients and methods: A prospective, longitudinal, double-blind, comparative study was designed which included patients with recent diagnosis of ICSC from June 2002 to October 2003. They were randomly divided into: Group I which received treatment with topical brinzolamide 2% bid; and Group II, which received polyvinyl alcohol (placebo) bid. We studied symptomatic and clinical recovery time, complications, fluorangiografic hot spots and visual acuity.
Results: We included 16 patients; 3 were excluded and 7 were included in group I. Six were included in group II. We found a statistic significant difference (p=0.03) in time of clinic recovery and a tendency toward symptomatic recovery (p=0.07).
Complications were seen more often in group II (p= 0.03) with statistical significance. No adverse effects were seen with the use of brinzolamide. Good tolerance was reported.
Conclusions: Brinzolamide may shorten the time of recovery of ICSC, prevent complications and is safe to use.


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