Rivera MCG, López CA, Rodríguez PMA, Montiel GE

Language: Spanish
References: 10
Page: 170-173
PDF size: 311.20 Kb.

ABSTRACT

Background: To describe the clinical variables and treatment results of patients with esthesioneuroblastoma at otolaryngology and head and neck surgery service of Hospital Central Militar, Mexico.
Material and methods: The study was done with the data of patients diagnosed from January 2000 to January 2006, at otolaryngology and head and neck surgery service of Hospital Central Militar, Mexico. Data obtained were: name, register, sex, age, image studies, histopathological diagnosis, tumor classification, surgical procedure, complementary treatment and complications.
Results: Five patients were included: 60% with Kadish C classification (T3 of Dulguerov) and 40% Kadish B (T1 of Dulguerov). Treatment was exclusively surgical in 40% of patients and surgical plus radiotherapy in 60%. Eighty percent of patients did not have recurrences and 20% (1) had metastasis in the neck.
Conclusions: The most proper treatment of this study was: cranio-facial resection by combined approach (open plus endoscopic). In advanced stages radiotherapy was added; however, this article presents few cases to establish statistically significant conclusions.

REFERENCES

1. Randall DA. The nose and paranasal sinuses. In: Lee KJ. Essential otolaringology: Head and neck surgery. 8th ed. New York: McGraw-Hill, 2003;pp:711,1035.

2. Thane CD. Neoplasms of the nasal cavity. In: Cummings CW. Otolaryngology head and neck surgery. 3th ed. Saint Louis: Mosby, 1998;pp:896-7.

3. Kaplan MJ. Lesions of the anterior skull base. In: Lalwani AK. Current: diagnosis and treatment in otolaringology head and neck surgery. New York: McGraw-Hill, 2004;p:805.

4. Lund JV, Howard DJ, Wei WI, Spittle L. Olfactory neuroblastoma: Past, present, and future? Laryngoscope 2003;13:(3):502-7.

5. Devaiah AK, Larsen C, Tawfik O, O’Boynick P, Hoover LA. Esthesioneuroblastoma: Endoscopic nasal and anterior craniotomy resection. Laryngoscope 2003;113(12):2086-90.

6. Argiris A, Dutra J, Tseke P, Haines K. Esthesioneuroblastoma: The Northwestern University experience. Laryngoscope 2003;113:(1):155-60.

7. Simon JH. Esthesioneuroblastoma: The University of Iowa experience 1978-1998. Laryngoscope 2001;111(3):488-93.

8. Shah JP, Galicih JH. Craniofacial resection for malignant tumors involving the anterior skull base. Arch Otolaringol 1997;123(12):1312-7.

9. Levine PA, Gallagher R, Cantrell L. Esthesioneuroblastoma: Reflections of a 21-year experience. Laryngoscope 1999;109(10):1539-43.

10. Diaz EM, Johnighan RH, Pero C, et. al. Olfactory neuroblastoma: the 22-year experience at one comprehensive cancer center. Head Neck 2005;27(2):138-49.