González EM, Ordaz FJC, Mora MI, Juárez EJC, González RM, Fernández H

Language: Spanish
References: 19
Page: 38-41
PDF size: 37.62 Kb.

ABSTRACT

Objective: To describe ocular manifestations of systemic lupus erythematosus in children and to examine the correlation with inflammatory systemic disease.
Material and methods: Observational, descriptive, transverse and prospective study. Clinical data regarding their systemic disease and disease activity were recorded and a full ophthalmic examination carried out from May to December 2006.
Results: 20 patients were recruited. Of these, 17 were females with a mean age of 155±57months and 3 were male with 123±101months. 16 (80%) patients had systemic activity and ocular manifestations: amaurosis fugax (1), blepharitis (2), dry eye (8), conjunctivitis (1), episcleritis (2), retinopathy – cotton-wool spots (2), maculopathy -not associated with cloroquine- (1) retinal pigment epithelium disorder –periphery- (2) and cataracts -associated with corticosteroid use- (3). Not statistical significance in the correlation with systemic activity and specific ocular manifestations.
Discussion and conclusion: Children with systemic lupus should be evaluated periodically by a pediatric ophthalmologist by virtue of that a high percentage of patients presents ocular pathology, independently that the lupus have or not activity.

REFERENCES

1. Lang BA, Silverman ED. A clinical overview of systemic lupus erythematosus in childhood. Pediatrics in Review 1993;14:194-201.

2. Tan EM y cols. The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum 1982;25:1271.

3. Cortés-Grimaldo RM., Espinosa-Rosales F. Actividad clínica de Lupus eritematoso sistémico en pacientes pediátricos mexicanos. Correlación entre la evaluación del médico y la obtenida por la aplicación de cinco índices de actividad. Instituto Nacional de Pediatría. Universidad Nacional Autónoma México. México 2003.

4. Arévalo JF, Lowder CT, Muci-Mendoza R. Ocular manifestations of systemic lupus erythematosus. Curr Opin Ophthalmol 2002; 13:404-10.

5. Soo MPK, Chow SK y cols. The spectrum of ocular involvement in patients with systemic lupus erythematosus without ocular symptoms. Lupus 2000; 9:511-514.

6. Yap EY, Au Eong KG y cols. Ophthalmic manifestations in asian patients with systemic lupus erthematosus. Singapore Med J 1998; 39:557-559.

7. Peponis V, Kyttaris VC y cols. Ocular manifestations of systemic lupus erythematosus: a clinical review. Lupus 2006;15:3-12.

8. Chan DQ. Neurologic, ophthalmic, and neuropsychiatric manifestations of pediatric systemic lupus erythematosus. Optom Vis Sci 2000; 77:388-94.

9. Read RW, Chong LP et al. Occlusive retinal vasculitis associated with systemic lupus erythematosus. Arch Ophthalmol 2000; 118:588-89.

10. Cunningham ET, Alfred PR, Irvine AR. Central serous chorioretinopathy in patients with systemic lupus erythematosus. Ophthalmology 1996; 103:2081-90.

11. Jabs DA, Hanneken AM y cols. Choroidopathy in systemic lupus erythematosus. Arch Ophthalmol 1988; 106:230-34.

12. Jost BF, Olk RJ y cols. Anterior segment ischaemia following laser photocoagulation in a patient with systemic lupus erythematosus. Br J Ophthalmol 1988; 72:11-16.

13. Sekigawa I, Yoshiike T y cols. Allergic disorders in systemic lupus erythematosus: prevalence and family history. Lupus 2002; 11(7):426-429.

14. Soo MP., Chow SK y cols. The spectrum of ocular involvement in patients with systemic lupus erythematosus without ocular symptoms. Lupus 2000; 9 (7):511-4.

15. Montehermoso A., Cervera R, Font J y cols. Association of antiphospholipid antibodies with retinal vascular disease in systemic lupus erythematosus. Semen Arthritis Rheum 1999;28(5):326-32.

16. Ushiyama O, Ushiyama K, Koarada S y cols. Retinal disease in patients with systemic lupus erythematosus. Ann Rheum Dis 200; 59(9):705-8.

17. Cobo-Soriano R, Sánchez-Ramón AMJ y cols. Antiphospholipid antibodies and retinal thrombosis in patients without risk factors: a prospective case-control study. Am J Ophthalmol 1999; 128(6):725-32.

18. Ermakova NA, Alekberova ZS, Kosheleva NM y cols. Characteristics of retinal vascular involvement in systemic lupus erythematosus. Vestn Oftalmol 2001; 117 (2):21-4.

19. Lanham JG, Barrie Ty cols. SLE retinopathy: evaluation by fluorescein angiography. Ann Rheum Dis 1982; 41(5):473-8.