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Revista Mexicana de Oftalmología

Anales de la Sociedad Mexicana de Oftalmología y Archivos de la Asociación Para Evitar la Ceguera en México
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2008, Number 3

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Rev Mex Oftalmol 2008; 82 (3)

Uso de toxina botulínica subtenoniana en parálisis del sexto nervio craneal

Lozano TA, Hernández OT, Castillo OC, Fuente TMA
Full text How to cite this article

Language: Spanish
References: 10
Page: 163-165
PDF size: 48.41 Kb.


Key words:

Sixth nerve cranial palsy, botulinum toxin, paralytic strabismus, diplopia.

ABSTRACT

Objective: To determine the efficacy of subtenonian botulinum toxin in the treatment of sixth cranial nerve palsy.
Methods: 20 files, from January 2004 to November 2006, of patients with sixth cranial nerve palsy of any etiology were analyzed. Patients were treated with subtenonian injection of botulinum toxin in the medial rectus. Data of patients regarding age, affected muscle, primary position, amount of duction limitation, presence of diplopia after and before treatment, and number of applicated doses were analyzed.
Results: The average age was 58.15 years (13 to 87 years) ten patients (50%) were male and ten (50%) were female. Twenty five doses were applied, 20 (75%) as first application and 5 (15%) as second due to absence of improvement. All patients (100%) had limitation of duction. After the treatment 15 patients (75%) had no limitation. Before the application none of the patients had ocular alignment, at the end of the treatment 18 patients (90%) obtained it.
Conclusions: The use of subtenonian botulinum toxin brings a fast and effective improvement in the treatment of sixth cranial nerve palsy of any etiology.


REFERENCES

  1. Tasman W. Duane’s Ophthalmology. Lippincott Williams & Wilkins, 2006.

  2. Romero D. Estrabismo.1ª. Ed. Auroch México, 2000; pag. 321-327.

  3. BOTOX® [package insert]. Irvine, CA; Allergan Pharmaceuticals, 2004.

  4. Kao LY, Chao AN. Subtenon injection of botulinum toxin for treatment of traumatic sixth nerve palsy. Ped Ophthal Strabismus 2003; 40(1):27-30.

  5. Quah BL. A review of 5 years’ experience in the use of botulinium toxin A in the treatment of sixth cranial nerve palsy at the Singapore National Eye Centre. Singapore Med J 1999; 40(6):405-9.

  6. Holmes. Initial treatment outcomes in chronic sixth nerve palsy. J Jaapos 2002; 5(6):370-6.

  7. Chuenkongkaew W. Botulinum toxin treatment of the sixth nerve palsy: an experience of 5-year duration in Thailand. J Med Assoc Thai 2001; 84(2):171-6.

  8. Amorós-García S. Parálisis del sexto nervio: Factores influyentes en la eficacia del tratamiento con toxina botulínica subtenoniana. Acta Estrabótica Zaragoza 1997; XXXI(1).

  9. Smith A, Kettlewell B. Botullinum neurotoxins in therapeutical management of strabismus. Am J Ophthal 2004; 74(4):476-480.

  10. López-García JG. Tratamiento con toxina botulínica del estrabismo paralítico adquirido. Annals d’Oftalmologia 2004; 12(3):150-155.




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Rev Mex Oftalmol. 2008;82