2007, Number 04
Ginecol Obstet Mex 2007; 75 (04)
Cervical cancer and DNA microarrays: Tumor marker identification
Acevedo RCG, Álvarez E, Zafra RG, Álvarez NM, Gariglio P
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Microarray technology has remarkably accelerated the understanding of the molecular events of neoplasias. By means of gene expression profiles, a molecular subclassification of cancer patients and the identification of thousand of genes involved in this pathology have been achieved. Herein, the general use of DNA microarrays in cervical cancer tumorigenesis is reviewed. Finally, putative molecular tumour markers as useful factors in diagnosis, prognosis, and tailor-made therapy for this disease are proposed.
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