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2005, Number 1

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Med Sur 2005; 12 (1)

Acute lymphoblastic leukemia. A clinical case

Ruiz-Delgado GJ, Ricardo Sosa-Sánchez R
Full text How to cite this article

Language: Spanish
References: 6
Page: 44-46
PDF size: 37.57 Kb.


Key words:

Acute leukemia, leukemia lymphoblastic.

ABSTRACT

This 23 year-old female was admitted to the hospital because of abdominal pain, nausea, vomiting, dyspnea, fever and sweating; she had lost 20 kg in a two-year period. On physical examination lymph node enlargements were found as well as liver and spleen enlargements. The CBC disclosed pancytopenia: Anemia of 8.6 g/dl, leukopenia of 1,700 and thrombocytopenia of 64,000. The bone marrow aspirate study showed heavy infiltration by lymphoblasts exhibiting the antigens CD10, CD19 and CD20, consonant with B-cell line acute lymphoblastic leukemia. The patient was treated with combined chemotherapy which included vincristine, asparaginase, mitoxantrone and dexametasone; she has had an initial good response.


REFERENCES

  1. Ruiz-Argüelles GJ, McArthur JR. Leucemias agudas. En: Fundamentos de Hematología, 3a. edición. AMEH. Ruiz-Argüelles GJ. Editor. Editorial Médica Panamericana. México. 2003: 225-245.

  2. Ruiz-Argüelles GJ, Ruiz-Argüelles A, Pérez-Romano B, López-Martínez B, López-Tapia JD, Lobato-Mendizábal E, Marín-López A. Immunologic classification of acute leukemia in Mexico according to the First Latin American Consensus Conference for Immunophenotyping of Leukemia. Cancer Res Ther Control 1999; 10: 163-166.

  3. Ruiz-Argüelles GJ, Garcés-Eisele J, Reyes-Núñez V, Pérez-Romano B, Ruiz-Argüelles A, Ramírez-Cisneros F, López-Martínez B, López-Tapia JD, Rivadeneyra-Espinoza L. Assessment of residual disease in acute leukemia by means of polymerase chain reaction: A prospective study in a single institution. Rev Invest Clin Mex 2000; 52: 118-124.

  4. Gómez-Almaguer D, Montemayor J, González-Llano O, Ruiz-Argüelles GJ, Betz NL, Marfil-Rivera J. Leukemia and nutrition IV. Improvement in the nutritional status of children with standard-risk acute lymphoblastic leukemia is associated with a better tolerance of continuation chemotherapy. Int J Ped Hematol/Oncol 1995; 2: 53-56.

  5. Romero F, Paredes R. Definición de riesgos en leucemia aguda. En: Ruiz-Argüelles GJ, San Miguel FJ (editores). Actualización en leucemias. Editorial Médica Panamericana. México 1996: 41-50.

  6. Pérez-Tamayo R. Introducción al estudio de las leucemias agudas. En: Ruiz-Argüelles GJ, San Miguel FJ (editores). Actualización en leucemias. Editorial Médica Panamericana. México 1996: 9-11.




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C?MO CITAR (Vancouver)

Med Sur. 2005;12