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2005, Number 1

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Med Crit 2005; 19 (1)

Rhabdomiolysis. Case report and review of literature

Gutiérrez LP, Elizondo ME, Gutiérrez JP
Full text How to cite this article

Language: Spanish
References: 8
Page: 31-36
PDF size: 70.64 Kb.


Key words:

Rhabdomyolysis, fenoverine, physiopathology, diagnosis, complications, treatment.

ABSTRACT

Introduction: Rhabdomyolysis is an infrequent pathology in the intensive care unit.
Objective: To present a case of rhabdomyolysis and a review of literature.
Design: Case report.
Setting: ICU of a private hospital, Monterrey, Nuevo Leon; Mexico.
Patient: A 59-yrs-old woman with history of abdominal pain who received fenoverine during three days. Twenty four hours later she had muscular pain and generalized weakness. She was admitted to the ICU detecting acute renal failure.
Interventions: Intermitent hemodialysis (five procedures).
Results: During the ICU stay was found: high elevated concentration of creatinine (3-6.6 mg/dL), BUN (27-96 mg/dL, CPK-MB (1,531-10,080 UI/L) in blood, and a decrease of hemoglobine values (8.5 g/dL). A muscle biopsy was compatible with rhabdomyolysis.
Conclusions: Rhabdomyolysis due to fenoverine is rare and may be associated to acute renal failure.


REFERENCES

  1. Visweswaran P, Guntupalli J. Environmental emergencies. rhabdomyolysis. Critical Care Clinics 1999;15(2):416-428.

  2. Vanholder R, Sukru Sever M. Disease of the month. Rhabdomyolysis. Journal of the American Society of Nephrology 2000;11(8):1-17.

  3. Holt S, Moore K. Pathogenesis of renal failure in rhabdomyolysis: The role of Myoglobin. Exp Nephrol 2000;8:72-76.

  4. Kuwagata Y, Oda J, Tanaka H, Iwai A, Matsuoka T, Takaoka M. Analysis of 2,702 traumatized patients in the 1995 Hanshin-Awaji earthquake. J Trauma 1997;43: 427-432.

  5. Gabow PA, Kahney WD, Kelleher SP. The spectrum of rhabdomyolysis. Medicine 1982;61:141-152.

  6. Knochel JP. Mechanisms of rhabdomyolysis. Curr Opin Rheumatol 1993;5:725-731.

  7. Jouglard J, Kozak-Ribbens G. Research into individual predisposition to develop acute rhabdomyolysis attributed to fenoverine. Hum Exp Toxicol 1996;15(10):815-20.

  8. Chariot P, Ratiney R, Le Maguet F. Fenoverine-induced rhabdomyolysis. Hum Exp Toxicol 1995;14(8):654-6.




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C?MO CITAR (Vancouver)

Med Crit. 2005;19