Morillo-Montañés V, Armario HJC , González CA, Fernández-Vozmediano JM

Language: Spanish
References: 16
Page: 291-295
PDF size: 301.60 Kb.

ABSTRACT

TLipo-membranous panniculitis or membrano-cystic steatonecrosis is an alteration of the adipose tissue. Sclerotic plaques with tendency to become chronic, do usually appear located on the lower area of the legs. It is almost exclusive in female mostly obese and diabetic and with a severe component of venous stasis. It has the histologic features of a lobule panniculitis, cystic cavities surrounded by fatty tissue with clear signs of steatonecrosis are formed by confluence. We present the case of a 36 years old female who developed a painful lesion on the location of a previous lesion, it had numerous nodule-cystic formations we noticed on palpation. The dermato-pathological study showed up the presence of cystic structures located on the lobules and at the level of the septum, surrounded by fatty tissue, with clear signs of steatonecrosis, a significant presence of frothy histiocytes and breakage of the cellular membranes with formation of micro-cysts. The cystic cavities were limited in their inner side by a serpiginous membrane, no nuclear, homogeneous and eosinophilic, PAS+, with a granulated appearance. It even formed in some areas pseudo-papillae, which projected themselves towards the interior of the cyst. It has been suggested that ischemia is the main pathogenic cause for lipo-membranous panniculitis, although other reasons are also considered such as a previous trauma. Nowadays, we do not still know the reason why these changes are more prominent in certain patients than in other with the same disease.

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