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>Journals >Cirujano General >Year 2008, Issue 4


Méndez MMG, . Montalvo-Javé EE, Wintergerst TE, Téllez SM, Castell RA, Gómez CA, Laguna HG, Osuna FR, Brechú FAE
Cicatrizing effect of an ointment prepared of Dorstenia drakena L. (Moraceae) in skin hurts
Cir Gen 2008; 30 (4)

Language: Español
References: 16
Page: 204-210
PDF: 4. Kb.


Full text




ABSTRACT

Objective: To evaluate the cicatrizing effect of the ointment made of rhizomes of Dorstenia drakena (Moraceae), commonly known as “Gallito” in Xochipala, Guerrero State, Mexico, which is used in Mexican traditional medicine for the treatment of superficial hurts. Design: This was an experimental, prospective, and comparative study. Material and methods: It was practiced an incision of 2.5 cm long in the skin on Wistar male rat backs weighing from 200 to 250 g. The incision was not sutured and it was applied 0.35 g of each of the following four daily treatments: I. Vaseline as the control treatment; II. Ointment along with 5 g of Sodium Acexamate (RecoverónMR, Armstrong Laboratorios de México, S.A de C.V) as the positive control; III. Ointment elaborated without rhizomes of D. drakena, as the negative control; and IV. Ointment elaborated with 100 g of grinded rhizomes of D. drakena, as the experimental treatment. With the purpose of evaluating the cicatrizing effect of the ointment prepared with rhizomes of D. drakena, the size of the hurt was measured daily. Samples of paraffin cuts of the cicatrizing tissue, stained by Masson, were taken at 15- and 30-treatment days and analyzed by means of an optical microscope. No infection was present in none of the hurts. Conclusiones: La cicatriz de los animales del grupo IV, tratados con pomada de rizoma de gallito, fue menos visible respecto a los otros tratamientos. La citometría reveló mayor cantidad de fibroblastos y linfocitos con el tratamiento IV, sugiriendo mejor calidad de la herida.


Key words: Hurts, skin, cicatrization, Dorstenia drakena, infection, surgery.


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>Journals >Cirujano General >Year 2008, Issue 4
 

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