Mendoza CF, Valladares GV, Ballesteros MA, Ayala CMM

Language: Spanish
References: 20
Page: 178-181
PDF size: 165.52 Kb.

ABSTRACT

Incidence of Behçet disease in USA is 0.12 in 100,000; but in Mexico there are just two isolated cases. This paper reports a case of a 30 year-old female, who, when 26, had vaginal ulcers. She received antimicrobial therapy during four years. In March 2007 she came to author’s hospital with a cervical vaginitis diagnose study, and presenting thorax with venous collateral circulation secondary to superior and inferior cava vein thrombosis. Colposcopy and vaginal wall biopsy were practiced and found chronic ulcer with vascular damage; oral ulcers were found too, and Pathergy test was positive. Currently there is no ocular damage. Patient received azathioprine therapy without improvement, later she received anticoagulant therapy with corticoids and has good evolution.

REFERENCES

1. Kastner DL. Intermitter and periodic arthritic syndromes. In: Koopman WJ, editor. Arthritis and allied conditions: a textbook of rheumatology. 13th ed. Vol 1. Baltimore: Williams & Wilkins 1997;pp:1279-306.

2. Kaklamani VG, Variopoulos G, Kaklamanis PG. Behçet disease. Semi Arthritis Rheum 1998;27:197-219.

3. Mizuki N, Inoco H, Ohno S. Pathogenic gene responsible for predisposition to Behçet’s disease. Int Rev Immunol 1997;14:33-48.

4. Nussenblatt RB. Uveitis in Behçet’s disease. Int Rev Immunol 1997;14:67-79.

5. Nakae K, Masaki F, Hashimoto T, Inaba G, Mochizuki M, Sakane T. Recent epidemiological features of Behçet’s disease in Japan. In: Wechsler B, Godeau P, eds. Behçet’s disease. Amsterdam: Excerpta Medica, 1993;pp:145-51.

6. Zouboulis CC, Kotter I, Djawari D, et al. Epidemiological features of Adamantiades- Behçet’s disease in Germany and in Europe. Yonsei Med J 1997;38:411-22.

7. Dilsen N, Konice M, Aral O, Ocal L, Inanc M, Gill A. Risk factors for vital organ involvement in Behçet’s disease. In: Wechsler B, Godeau P, eds. Behçet’s disease. Amsterdam: Excerpta Medica 1993;pp:165-9.

8. Ohno S, Ohguchi M, Hirose S, Matsuda H, Wakisaka A, Aizawa M. Close association of HLA. Bw51 with Behçet’s disease. Arch Ophthalmol 1982;100:1455-8.

9. Sakane T. New perspective on Behçet’s disease. Int Rev Immunol 1997;14:89-96.

10. Lehner T. The role of heat shock protein, microbial and autoimmune agents in the etiology of Behçet’s disease. Int Rev Immunol 1997;14:21-32.

11. Hamuryudan V, Yurdakul S, Ozbakir F, Yazici H, Hekim H. Monozy-gotic twins concordant for Behçet’s syndrome. Arthritis Rheum 1991;34:1071-2.

12. Gul A, Inanc M, Ocal L, Aral O, Garin M, Konicc M. HLA-B15 negative monozygotic twins discordant for Behçet’s disease. Br J Rheumatol 1997;36:922-3.

13. Zouboulis CC, Buttner P, Djawari D, et al. Keitel W, et al. HLA-class antigens in German patients with adamantiades-Behçet disease and correlation with clinical manifestations. In: Wechsler B, Godeau P, editors. Behçet’s disease. Amsterdam: Excerpta Medica, 1993;pp:175-80.

14. Inhaba G. Clinical features of neuro- Behçet’s syndrome. In: Lehner T, Barnes CG, eds. Recent advances in Behçet’s disease. London: Royal Society of Medicine Services, 1986;pp:235-46.

15. Ehrlich GE. Vasculitis in Behçet’s disease. Int Rev Immunol 1997;14:81-8.

16. Yamashita N, Kaneoka H, Kaneko S, et al. Role of gamma delta T lymphocytes in the development of Behçet’s disease. Clin Exp Immunol 1997;107:241-7.

17. Mochizuki M, Suzuki N, Takeno M, Nagafuchi H, et al. Fine antigen specificity of human gamma delta T cell lines (V gamma 9+) established by repetitive stimilation with a serotype (KTH. I) of a gram-positive bacterium, Streptococcus sanguis. Eur J Immunol 1994;24:1536-43.

18. Sakane T, Suzuki N, Tsuchida T, Takada S, et al. Analysis of interleukin-2 activity in patients with Behçet’s disease: ability of T cells to produce and respond to interleukin-2. Arthritis Rheum 1986;29:371-8.

19. Suzuky N, Sakane T, Ueda Y, Tsunematsu T. Abnormal B cell function in patients with Behçet’s disease. Arthritis Rheum 1986;29:212-9.

20. Sakane T, Kotani H, Takada S, Tsunematsu T. Functional aberration of T cell subsets in patients with Behçet’s disease. Arthritis Rheum 1982;25:343-51.