2008, Number 4
Acta Pediatr Mex 2008; 29 (4)
González-Saldaña N, Hernández-Orozco HG, Castañeda-Narváez JL, Barbosa-Arzate P, Lombardo-Aburto E, Girón-Hernández JA
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ABSTRACTBackground: Burkholderia cepacia is non fermenting Gram negative bacillus, responsible for nosocomial bacteriemia outbrakes. We report outbrakes of Burkholderia cepacia at the Instituto Nacional de Pediatría. Despite the investigation the source of the B. cepacia outbrake remained unknown. Method: Between November 2003 and January 2006 the Laboratory of Bacteriology obtained B. cepacia from blood cultures of three hospitalized patients in the Intensive Care Unit, Department of Cardiovascular Surgery, Pneumology and Neonatology Units. A retrospective study was done in order to identify an epidemiologic relation and probably risk factors. Environmental cultures were taken. We describe B. cepacia characteristics of the cases. Results: Seven patients had B. cepacia in the first outbrake; five cases in the second outbrake in the Department of Cardiovascular Surgery and three B. cepacia infections in the third outbrake.Conclusion: Early detection of outbrakes is important in order to identify the cause and to prevent future events. B. cepacia was sensitive to levofloxacin, cefephim, and meropenem in the three outbrakes. In the first one sentivity to trimetroprim sulfamethoxazole was observed which was not seen in the second an third outbrakes.