2005, Number 2
Massive pulmonary tumoral embolism: Fatal complication in a case of extra skeletal osteosarcoma. A case report and review of literature
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ABSTRACTPulmonary tumoral embolism caused by osteosarcoma is a rare but lethal complication. Only seven cases have been reported. Dyspnea, chest pain and sudden anxiety are the main clinical manifestations due to obstruction in variable degree of pulmonary arteries by tumor emboli. We report a case of a 17 year old woman with soft tissues chondroblastic osteosarcoma of left thigh who surffed intrahospitalary sudden death. At the autopsy study there were some pulmonary artery branches completely occluded by chondroid emboli and bilateral pulmonary infarcts were also present. Pulmonary artery bifurcation was occluded by a tumor which came from the right ventricle. We compared our findings with those of literature and observed that chondroblastic variety of osteosarcoma is the most related with pulmonary tumoral embolism, most commonly in young women. Our case is the first reported in which the tumor was originated in soft tissue.
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