Maldonado ÁM, Enriquez LJ, Castellanos LJ, Gutiérrez GFA, Garduño AL, Castell CR, Jaspersen GJ

Language: Spanish
References: 7
Page: 83-87
PDF size: 173.18 Kb.

ABSTRACT

Background. Urinary stone is a common condition affecting up to 8 to 15% of the population. Ureteral stones occupy an important place in daily urological practice, acounting up to 15% of this practice. There is a conservative medical treatment for ureteral stones located in the lower ureter.
Materials and methods. A total of 99 patientes with stones less than 10 mm located in the lower ureter were enrolled in the study and were randomly divided into 3 groups. Group 1 (n=35) and group 2 (n=32) received daily oral treatment of 4 mg parametasone , maximum 21 days; 10 mg ketorolac three times every day for 5 days; 250 mg ciprofloxacyn twice at day for 8 days. In addition group 1 patients received l daily oral therapy of 0.4 mg tamsulosin maximum 21 days and group 2 patients received daily oral treatment of 20 mg nifedipine maximum 21 days. Group 3 received ciprofloxacyn and ketorolac . All patients also received 2 l. of low mineral content water daily. Statistical analyses were performed using the chi-square test and Fisher´s exact test.
Results. Expulsion was observed in 27 of 35 patients in group 1 (77.14%), 16 of 32 patients in group 2 (50%), in 11 of 32 patients in group 3 (34.3%). Average expusion time for groups 1 to 3 was 18.2, 19.3 and 20 days respectively. A statiscally significant difference was noted between the 3 groups. A number of 2 patients jump off the treatment for adverse effects.
Conclusions. Medical treatment with tamsulosin proved to be safe an effective as demonstrated by the increased stone expulsion rate. Moreover treatment with tamsulosin did not have adverse effects. Finally the cost with this conservative medical management is low versus surgery.

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