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Revista Mexicana de Oftalmología

Anales de la Sociedad Mexicana de Oftalmología y Archivos de la Asociación Para Evitar la Ceguera en México
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2008, Number 6

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Rev Mex Oftalmol 2008; 82 (6)

Uso de teicoplanina en endoftalmitis infecciosa. Reporte de un caso

Hernández DMSE, Paez MRM
Full text How to cite this article

Language: Spanish
References: 9
Page: 407-409
PDF size: 65.22 Kb.


Key words:

Teicoplanine, endophthalmitis, vancomycin.

ABSTRACT

Introduction: Intravitreal injection of antibiotics remains as the mainstay of therapy of postchirurgic endophthalmitis. Bacterial resistance, however, is still a drawback in adequate response to treatment. Teicoplanin, a glucopeptide antibiotic, might be a viable therapeutic option in these cases.
Case report: A 65 female patient had an endophthalmitis secondary to Staphylococcus aureus and was treated with teicoplanine showing a favorable outcome, pain remission as well as the infectious process.
Discussion: Although vancomycin remains as the first line intravitreal antibiotic against infectious endophthalmitis caused by Gram positive bacteria, teicoplanine exhibits similar efficacy, theoretically more active against vancomycinresistant strains.


REFERENCES

  1. Allen HF. Symposium: Postoperative endophthalmitis. Introduction: incidence and etiology. Ophthalmology 1978; 85:317-19.

  2. Baum J, Peyman GA, Barza M. Intravitreal administration of antibiotics in the treatment of bacterial endophthalmitis. III. Consensus. Surv Ophthalmol 1982; 26:204-6.

  3. Endophthalmitis Vitrectomy Study Group. Results of the Vitrectomy Study. A randomized trial of immediate vitrectomy and of intravenous antibiotics for the treatment of postoperative bacterial endophthalmitis. Arch Ophthalmol 1995; 113:1479-1496.

  4. Smith MA, Sorenson JA, D’Aversa G y cols. Treatment of meticillin-resistant Staphylococcus epidermidis endophthalmitis with intravitreal vancomycin and intravitreal dexamethasone. J Infect Dis 1997; 175:462-466.

  5. Juárez-Verdayes MA, Reyes-López MA, Cancino-Díaz ME y cols. Isolation, vancomycin resistance and biofilm production of Staphylococcus epidermidis from patients with conjunctivitis, corneal ulcers, and endophthalmitis. Rev Latinoam Microbiol. 2006; 48(3-4):238-46.

  6. Briggs MC, McDonald P, Bourke R, Smith G, McGalliard JN, Wong D. Intravitreal penetration of teicoplanin. Eye 1998; 12(Pt 2):252-5.

  7. Carney M, Kao G, Peyman GA, Fiscella R, Staneck J. The intraocular penetration and retinal toxicity of teicoplanin. Ophthalmic Surg. 1988; 19(2):119-23.

  8. Chambers HF, Sande MA. Teicoplanin versus nafcillin and vancomycin in the treatment of experimental endocarditis caused by methicillin-susceptible or –resistant Staphylococcus aureus. Antimicrob Agents Chemother 1984; 26(1):61-4.

  9. Benz MS, Scout IU, Flynn HW Jr y cols. Endophthalmitisisolates and antibiotic sensitivities: a 6-year review of culture- proven cases. Am J Ophthalmol 2004; 137:38-42.




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C?MO CITAR (Vancouver)

Rev Mex Oftalmol. 2008;82