Gómez-Valcárcel M, Rodríguez-Reyes AA, Vanzzini-Zag V, Uguette Angel-Muñoz E

Language: Spanish
References: 5
Page: 116-118
PDF size: 125.11 Kb.

ABSTRACT

Keratomycosis in Mexico is caused mainly by phylamentous fungi. The most important risk factors are ocular injury and corneal ulcer contamination by dirt or vegetable material.
Herein the case report of a patient with keratomycosis by Fusarium solani due to ocular trauma with a crack-cocaine rock. The patient had poor treatment response requiring a corneal transplant and evisceration later on.
Cocaine has an anesthetic effect on corneal tissue, thereby inhibiting neutrophil phagocytosis and phagolysosomal acidification, hampering immune response and enhancing risk of infection.

REFERENCES

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3. Mukunda BN, Callahan JM, Hobbs MS, West BC. Cocaine inhibits human neutrophil phagocytosis and phagolysosomal acidification in vitro. Immunopharmacol Immunotoxicol 2000; 22(2):373-86.

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