Vadillo-Ortega F, Córdoba K, Quezada A, Beltrán-Montoya J, Gutiérrez-Corchado S, Menocal-Tobías G

Language: Spanish
References: 9
Page: 108-112
PDF size: 66.95 Kb.

ABSTRACT

Objective: To determine the relationship among oncofetal fibronectin (Oncfn) expression and metalloproteinase-9 (MMP-9) in vaginal secretions of women on different labor stages.
Methods: It was a cross-sectional clinical study that included women with and without delivery, stratified according to the Bishop scale. A sample of vaginal secretions was taken and Oncfn was determined by ELISA and MMP-9 by zimography.
Results: It was documented that Oncfn and MMP-9 concentrations increased along delivery, however, the expression of the MMP-9 in vaginal secretions was present from the first phases of development of labor, as long as the fnOnc makes it in a late time, once the delivery has progressed.
Conclusions: The Oncfn and the MMP-9 seems to be biological markers of the progress of delivery and its appearance in vaginal secretions very probably reflect the degradation phenomenon on membranes and placenta’s connective tissue. MMP-9 becomes positive before the Oncfn.

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