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>Journals >Gaceta Médica de México >Year 2008, Issue 5

Muñoz-Espinosa LE, Martínez-García A, Castillo O, Cordero-Pérez P, Caballero-Mendoza E, Pérez-Rodríguez E, Hernández GMA, Elizondo-Riojase G, Escobedo-Villarreal M
Recidiva postrasplante de hepatopatías no virales
Gac Med Mex 2008; 144 (5)

Language: Español
References: 21
Page: 403-408
PDF: 112.81 Kb.

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Objective: We describe the recurrence of non-viral liver disease after orthotopic liver transplantation (OLT). Methods and Results: We studied 39 patients who received an OLT for non-viral chronic liver disease. Six (15.3%) of these patients presented disease recurrence after OLT, one following alcohol abuse, 3 presented autoimmune liver disease [2 received an OLT for primary biliary cirrhosis and recurred as autoimmune hepatitis (AIH) one patient had cryptogenic cirrhosis before OLT and recurred as AIH]. One patient showed recurrence of a non-alcoholic steatohepatitis (NASH). One patient received an OLT for cirrhosis secondary to the use of metothrexate and post OLT developed secondary biliary cirrhosis due to a choledocal stenosis in the anastomotic site. Conclusions: All patients described here displayed long term recurrence (after 11 months post OLT). The recurrence of alcoholism was 8.3% among patients transplanted for this condition. AIH was observed in 30% of cases and NASH in 20%. All three patients with autoimmune liver disease recurred with a different autoimmune disease post OLT.

Key words: Liver transplant, alcoholic liver disease, autoimmune hepatitis, non-alcoholic steatohepatitis, NASH, primary biliary cirrhosis.


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>Journals >Gaceta Médica de México >Year 2008, Issue 5

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