Encalada MLA, López AME, Mendoza GP, Liébano HE, Vázquez PV, Vera YG

Language: English/Spanish
References: 12
Page: 423-428
PDF size: 146.79 Kb.

ABSTRACT

The aim of this work was to determine the presence of ivermectin anthelmintic resistance in gastrointestinal parasitic nematodes in young cattle naturally infected in the state of Campeche, Mexico. This research was performed based on a survey of sanitary management to 35 cattlemen for the selection of suspicious herds with anthelmintic resistance problems. Calves from six to 12 months age were selected because no anthelmintic treatment had been given for at least 60 days and because they showed more than 200 eggs per gram of feces (epg) before treatment. Two groups of calves from seven to 13 each were randomly chosen; control group received no treatment, and treated group received ivermectin at a dose of 0.2 mg per kg of body weight, subcutaneously. Fourteen days after treatment, the epg number was determined and infective larvae genera were taxonomically identified. Data were analyzed using RESO program for anthelmintic resistance. The results indicated a concerning problem of ivermectin anthelmintic resistance in the evaluated cattle of five ranches with levels higher than 60%. The nematode genera identified before treatment were: Cooperia spp, Haemonchus spp and Oesophagostomum sp, and after treatment Cooperia spp still remained in five ranches, followed by Oesophagostomum sp and Haemonchus spp for two of the evaluated ranches. This research shows, for the first time in the state of Campeche, anthelmintic resistance in young cattle, as well as presence of gastrointestinal nematodes resistant to ivermectin.

REFERENCES

1. Coles GC. Cattle nematodes resistant to anthelmintics: why so few cases? Vet Res 2002;33:253-259.

2. Kaplan RM. Drug resistance in nematodes of veterinary importance a status report. Trend Parasitol 2004;20:477-481.

3. Fiel CA, Saumell CA, Steffan PE, Rodriguez EM. Resistance of Cooperia to ivermectin treatment in grazing cattle of the humid Pampa, Argentina. Vet Parasitol 2001; 97:231-219.

4. Wolstenholme AJ, Fairweather I, Prichard R, Von Samson-Himmelstjerna G, Sangster NC. Drug resistance in veterinary helminths. Trend Parasitol 2004;20: 469-476.

5. Mejía EF. Estudio recapitulativo de la distribución geográfica de helmintos y Eimeria spp de rumiantes domésticos en la República Mexicana (tesis de licenciatura). México, DF: Universidad Nacional Autónoma de México, 1986.

6. Instituto Nacional de Estadística, Geografía e Informática. Sistema Municipal de Base de Datos [Serie en línea] 2006 Sep. [citado 2006 sep 22]. Disponible en: http://www.inegi.gob.mx

7. Coles GC, Jackson F, Pomroy WE, Prichard RK, Samson-Himmelstjerna von G, Silvestre A et al. The detection of anthelmintic resistance in nematodes of veterinary importance. Vet Parasitol 2006; 136:167-185.

8. Veterinary International Cooperation Harmonization. Effectiveness of anthelmintics: Specific Recommendations for Bovine [online] 1999 Nov. [cited: 2006 Nov 16] Available from: www.vichsec.org/pdf/2000/GL12_ST7.pdf

9. Liébano HE. Identificación morfométrica de larvas infectantes de nematodos gastrointestinales y pulmonares en rumiantes domésticos de México. En: Vazquez PVM, editor. Diagnóstico y control de los nematodos gastrointestinales de los rumiantes en México. Morelos, México: INIFAP, 2004:26-77.

10. Anziani OS, Suarez V, Gulielmone AA, Warnke O, Grande H, Coles GC. Resistance to bencimidazole and macrocyclic lactone anthelmintics in cattle nematodes in Argentina. Vet Parasitol 2004;122:303-306.

11. Gasbarre LC, Smith LL, Lichtenfels JR, Pilitt PA. Identification of cattle nematode parasites resistant to multiple classes of anthelmintics in a commercial cattle population in the United States. 49th Meeting American Association of Veterinary Parasitologists; 2004 July 24-28; Philadelphia USA. Philadelphia USA: American Association of Veterinary Parasitologists, 2004:57.

12. Montalvo AX, López AME, Vázquez PVM, Liébano HE, Mendoza de GP. Resistencia antihelmíntica de nematodos gastroentéricos a bencimidazoles y lactonas macrocíclicas en la región noroeste del estado de Tlaxcala. Téc Pecu Méx 2006;44:81-90.