Feria-Segura D, Olvera-Morales G, Escobar-Escobar NF, Silva-Jiménez A

Language: Spanish
References: 15
Page: 171-176
PDF size: 116.18 Kb.

ABSTRACT

Objective: To compare the use of remifentanyl versus fentanyl in continuous infusion in laparoscopic cholecystectomy and to determine which drug presents a higher hemodynamic stability. Material and methods: The study included 45 patients under general anesthesia with elective surgery, ASA I, II, and III, being between 20 and 70 years old, divided in a randomized way into two groups: remifentanyl-sevofluorane (RS) and fentanyl-sevofluorane (FS), with 22 and 23 patients respectively. It was measured arterial pressure, cardiac frequency, oxygen saturation, carbon dioxide, and bispectral index (BIS) at one minute after laryngoscopy, first minute and 30 minutes after pneumoperitoneum, one minute of extubation and at discharge from the operation-room. The patients were medicated with 50 µg/kg of midazolam, induction with 1 mg/kg of propofol, narcosis with 5 µg/kg of fentanyl or 1 µg/kg of remifentanyl, neuromuscular block with 150 µg/kg of cisatracurium, maintenance with sevofluorane at 2 vol % and narcotic infusion, depending on the group. Results: For the RS group it was found a significant statistical difference (p ‹ 0.05) in cardiac frequency at one minute after the laryngoscopy, one minute and 30 minutes after the pneumoperitoneum and in the arterial pressure at 30 minutes after the pneumoperitoneum. Conclusions: Both of the agents demonstrated hemodynamic stability during the different periods of the laparoscopic cholecystectomy; however, in the group of remifentanyl there were statistical variations in the laryngoscopy and the pneumoperitoneum.

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