Hernández-Trejo M, Llano-Rivas I, Rivera RA, Aguinaga-Ríos M, Mayen-Molina DG

Language: Spanish
References: 0
Page: 125-132
PDF size: 85.13 Kb.

ABSTRACT

Objectives: Recognize the maternal risks factors that can be associated with perinatal mortality due to congenital birth defects in a reproductive health institution in México.
Methods: Maternal, neonatal and fetal variables were analyzed in a transversal study of cases with perinatal mortality with structural defects during a three year period at the Instituto Nacional de Perinatología (INPer), Mexico City.
Results: During the period 1999- 2001, 259 neonatal and 409 fetal deaths were reported. The principal cause of mortality death in the neonatal period found in 87 cases (33.5%) and the second cause of fetal death found in 59 cases (14.4%) was the presence of congenital birth defects. The risk of mortality with a structural defect was 14.6 times more in neonates (IC 95% .8, 122) and 38.3 times more in the fetal period (IC 95% 4.3, 311) when the mother was carrier of balanced structural chromosome rearrangement. The pregnant women with a maternal age of 17 or less years old had 14.2 times more risk of prenatal death with structural defects (IC 95% 2.5, 79), nevertheless they did not have an increased risk of neonatal death. When the maternal age was 35 years or more the risk of prenatal death was 500% more and have 730% more for neonatal death. The pregnant women with gestational diabetes or previous diabetes mellitus had 320% more fetal mortality because of major structural defects.
Conclusion: This study shows an increase of structural defects as primary cause of perinatal mortality according to other international statistics.