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2009, Number 3

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Rev Med Hosp Gen Mex 2009; 72 (3)

Ocular syphilis

Tenorio G, Ramírez SV, Sánchez CJ, Guido JMA
Full text How to cite this article

Language: Spanish
References: 8
Page: 149-154
PDF size: 262.82 Kb.


Key words:

Ocular syphilis, neurosyphilis, HIV and syphilis, stromal queratitis, acute glaucoma, bilateral papiledema.

ABSTRACT

Antecedents: Ocular syphilis is quite rare, it is equivalent to 1-2 % of the uveitis, is a simulatory disease that can be confused, especially in immunocompetent subjects, since the HIV positive patients are more susceptible to acquire it and consecuently it is suspected when the patient has neurosyphilis data. There are many clinical ways to manifest it, so that T. pallidum can affect every eye tissue. Objective: To describe the clinical findings in 5 patients diagnosed in a mean of 6 months. Methodology: Retrospective, observational case series study. We present the risk antecedents, and the general clinical and ophthalmic findings, laboratory data and photographic records.Results: Five patients, one female and four males, all of them had positive serum FTA-abs test, VDRL cephaloraquideum liquid was positive in 2 cases: one of patient had an iritis that evolved to pupilar block in one eye with advanced glaucoma, another patient without positive HIV presented oculomotor alterations, seizures, and conduct changes. Two patients with positive HIV had a bilateral papiledema, also peripheral vasculitis in one and oculomotor paralysis in the other. The female patient with positive HIV, presented deep stromal queratitis in one eye, pigment deposit in the cornea and in the iridocorneal angle, evolving with acute glaucoma in both eyes. Conclusions: Ocular syphilis is resurging before the high risk prevalence of sexual transmission diseases; we must suspect of it when the clinical data is not the characteristic one of other ocular inflammations, especially in HIV positive patients or with antecedents of sexual transmission diseases.


REFERENCES

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  3. Gaudio PA. Update on ocular syphilis. Curr Opin Ophthalmol 2006; 17: 562-566

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Rev Med Hosp Gen Mex. 2009;72