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ISSN 0188-2198 (Print)

2000, Number 4

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Rev Mex Cardiol 2000; 11 (4)

Anticoagulants

Navarro RJ, Valencia SJS, Abundes VA, Betancourt HL

Language: Spanish
References: 34
Page: 304-313
PDF size: 120.96 Kb.


ABSTRACT

Thrombin’s role in coagulation process is considered of great importance. This enzyme, wish has physiologic action of avoid extravasating of blood, back the vascular harm and promote reparing of the tissue, has and adverse demonstration too: thrombosis. Anticoagulants have a place very important in the therapeutics of several patologies, mainly in ischemic and vascular cardiac diseases. A long time ago we only had with standard heparin and coumarin (warfarin). Althoug were considered as select drugs for therapeutical of vasculary diseases. These drugs carry to adverse collateral effects. Nevertheless in the future there will possibility of to replace them by specific drugs to inhibit thrombosis. These drugs after results more secure to obtain the prevention and propagation of thrombos in the cardiovascular diseases. For example, the treatment indicated to ischemic cardiopaty is the thrombolisis add acetylsalicylic acid add heparin. Before to prescription one’s should do a carefulness analysis of patient.


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