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Revista ADM Órgano Oficial de la Asociación Dental Mexicana

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Órgano Oficial de la Asociación Dental Mexicana
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2003, Number 1

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Rev ADM 2003; 60 (1)

Abscence of serotonin in lateperiods during disjunction in rabbits

Méndoza-Oropeza L, Marichi-Rodríguez F, Flores-Luna MG
Full text How to cite this article

Language: Spanish
References: 35
Page: 5-13
PDF size: 151.72 Kb.


Key words:

Rapid maxillary expansion, inflammation, serotonin, immunohistochemistry.

ABSTRACT

The detection of serotonin in the mid palatal suture during the inflammatory process caused by rapid maxillary expansion (RME) was the purpose of the present study. Serotonin plays an important role as an inflammatory mediator in the inflammatory process, especially related with vascular permeability and pain production during the application of orthopedic forces, which is generated as an inflammatory response in the mid palatal suture. RME induces the physical maxillary separation with the application of techniques, which use forces that exceed the optimal limit to obtain orthodontic movements, producing an orthopedic response. These techniques are used in patients who need an increase in the maxillary width during the primary, mixed and permanent dentition; involving modifications in the middle palatal suture and other skeletal craneofacial structures. Twenty-four young male rabbits from the New Zealand stock were included in the present study, and a modified expansor was applied to the animals. The maxillary was dissected at inserted days 7,14 and 21 after the appliance was into the rabbit mouth. Slides were obtained; an indirect immunohistochemical technique using a monoclonal mouse antibody directed against serotonin. Serotonin was not detected in any of the experimental groups.


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Rev ADM. 2003;60