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2009, Number 6

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Bol Med Hosp Infant Mex 2009; 66 (6)

Coexistence of C677T and A1298C mutations in the MTHFR gene and thrombotic events

Baptista-Gónzalez H, Parra-Ortega I, López-Martínez B, Sánchez-Huerta JL
Full text How to cite this article

Language: Spanish
References: 25
Page: 582-585
PDF size: 89.10 Kb.


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REFERENCES

  1. Parra-Ortega I, López-Martínez B, González-Avila I, Rodríguez-Castillejos C, Jonguitud-Díaz V, Luna-Gaspar A, Sánchez-Huerta J, Vilchis-Ordóñez A. Coexistencia de las mutaciones C677T y A1298C en la enzima 5,10 metilentetrahidrofolato reductasa en pacientes pediátricos con trombosis. Bol Med Hosp Inf Mex 2009;66:229-233.

  2. Aguirre-Rodriguez AA, Martinez-de Villarreal LE, Velazco-Campos MR, Sampallo-Hernandez E, Esmer-Sanchez MC. Prevalence of polymorphism in the mthfr gene in a population sample from Nuevo León, México. Salud Pública Mex 2008;50:5-7.

  3. Pereira TV, Rudnicki M, Pereira AC, Pombo-de-Oliveira MS, Franco RF. 5,10-methylenetetrahydrofolate reductase polymorphisms and acute lymphoblastic leukemia risk: A meta-analysis. Cancer Epidemiol Biomarkers Prev 2006;15:1956-1963.

  4. Amorim MR, Lima MA, Castilla EE, Orioli IM. Non-latin european descent could be a requirement for association of ntds and mthfr variant 677c > t: A meta-analysis. Am J Med Genet A 2007;143A:1726-1732.

  5. Zintzaras E, Koufakis T, Ziakas PD, Rodopoulou P, Giannouli S, Voulgarelis M. A meta-analysis of genotypes and haplotypes of methylenetetrahydrofolate reductase gene polymorphisms in acute lymphoblastic leukemia. Eur J Epidemiol 2006;21:501-510.

  6. Ruiz-Argüelles GJ, Coconi-Linares LN, Garces-Eisele J, Reyes-Nunez V. Methotrexate-induced mucositis in acute leukemia patients is not associated with the mthfr 677t allele in México. Hematology 2007;12:387-391.

  7. Mejia-Arangure JM, Bonilla M, Lorenzana R, Juarez-Ocana S, de Reyes G, Perez-Saldivar ML, et al. Incidence of leukemias in children from El Salvador and México City between 1996 and 2000: Population-based data. BMC Cancer 2005;5:33.

  8. Keijzer MB, Borm GF, Blom HJ, Bos GM, Rosendaal FR, den Heijer M. No interaction between factor v leiden and hyperhomocysteinemia or mthfr 677tt genotype in venous thrombosis. Results of a meta-analysis of published studies and a large case-only study. Thromb Haemost 2007;97:32-37.

  9. Wu O, Robertson L, Twaddle S, Lowe GD, Clark P, Greaves M, Walker ID, Langhorne P, Brenkel I, Regan L, Greer I. Screening for thrombophilia in high-risk situations: Systematic review and cost-effectiveness analysis. The thrombosis: Risk and economic assessment of thrombophilia screening (treats) study. Health Technol Assess 2006;10:1-110.

  10. Den Heijer M, Lewington S, Clarke R. Homocysteine, mthfr and risk of venous thrombosis: A meta-analysis of published epidemiological studies. J Thromb Haemost 2005;3:292-299.

  11. Casas JP, Bautista LE, Smeeth L, Sharma P, Hingorani AD. Homocysteine and stroke: Evidence on a causal link from mendelian randomization. Lancet 2005;365:224-232.

  12. Cantu C, Alonso E, Jara A, Martinez L, Rios C, Fernandez M de L. Hyperhomocysteinemia, low folate and vitamin B12 concentrations, and methylene tetrahydrofolate reductase mutation in cerebral venous thrombosis. Stroke 2004;35:1790-1794.

  13. Ruiz-Argüelles GJ, Lopez-Martinez B, Valdes-Tapia P, Gomez-Rangel JD, Reyes-Nunez V, Garces-Eisele J. Primary thrombophilia in México. V. A comprehensive prospective study indicates that most cases are multifactorial. Am J Hematol 2005;78:21-26.

  14. Parra-Ortega I, López-Martínez B, González-Ávila I, Rodríguez-Castillejos C, Jonguitud-Díaz V, Luna-Gaspar A, Sánchez-Huerta JL, Vilchis-Ordóñez A. Coexistencia de las mutaciones C677T y A1298C en la enzima 5,10 metilentetrahidrofolato reductasa en pacientes pediátricos con trombosis. Bol Med Hosp Infant Mex 2009;66:229-233.

  15. Ruiz-Argüelles GJ. Trombofilia. Fundamentos de Hematología. México: Editorial Médica Panamericana. 2009; p. 287-295.

  16. Ruiz-Argüelles GJ, Garcés-Eisele J, Reyes-Núñez V, Ramírez-Cisneros F. Primary thrombophilia in México II: Factor V G1691A (Leiden), prothrombin G20210A and methylenetetrahydrofolate reductase C677T polymorphism in thrombophilic Mexican mestizos. Am J Hematol 2001;66:28-31.

  17. Ruiz-Argüelles GJ, López-Martínez B, Cruz-Cruz D, Reyes-Aulis MB. Primary thrombophilia in México III. A prospective study of the sticky platelet syndrome. Clin Appl Thromb Hemost 2002;8:273-277.

  18. Ruiz-Argüelles GJ, López-Martínez B, Valdés-Tapia P, Gómez-Rangel JD, Reyes-Núñez V, Garcés-Eisele J. Primary thrombophilia in México V: A comprehensive prospective study indicates that most cases are multifactorial. Am J Hematol 2005;78:21-26.

  19. Ruiz-Argüelles GJ, González-Carrillo ML, Estrada-Gómez R, Valdés-Tapia P, Parra-Ortega I, Porras-Juárez A. Primary thrombophilia in México. VI: Falta de asociación estadística entre las condiciones trombofílicas heredadas. Gac Med Mex 2007;4:317-322.

  20. Parra Ortega I, Estrada Gómez RA. Guzmán García MO. La mutación 677 C >T en la 5,10 metilentetrahidrofolato reductasa y el aumento de homocisteina en pacientes mexicanos. Med Inter Mex 2007;23:15-18.

  21. Djordjevic V, Stankovic M, Brankovic-Sreckovic V, Rakicevic L, Radojkovic D. Genetic Risk Factors for Arterial Ischemic Stroke in Children: A Possible MTHFR and eNOS Gene-Gene Interplay? J Child Neurol 2009;24:823-827.

  22. Ozyurek E, Balta G, Degerliyurt A, Parlak H, Aysun S, Gürgey A. Significance of Factor V, Prothrombin, MTHFR, and PAI-1 Genotypes in Childhood Cerebral Thrombosis. Clin Appl Thromb Hemost 2007;13:154-160.

  23. Kylan Lynch J, Christina J. Han, BA CJ, Nee LE, Nelson KB. Prothrombotic Factors in Children With Stroke or Porencephaly. Pediatrics 2005;116:447-453.

  24. Sucker C, Kurschat C, Farokhzad F, Hetzel GR, Grabensee B, Maruhn-Debowski B, et al. The TT genotype of the C677T polymorphism in the methylentetrahydrofolate reductase as a risk factor in thrombotic microangiopathies: results from a pilot study. Clin Appl Thromb Hemost 2009;15:283-288.

  25. Varga EA, Sturm AC, Misita CP, Moll S. Homocysteine and MTHFR Mutations: Relation to thrombosis and coronary artery disease. Circulation 2005;111:289-293.




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Bol Med Hosp Infant Mex. 2009;66