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ISSN 0185-6014 (Print)
Órgano oficial de difusión de la Federación Mexicana de Patología Clínica, AC y de la Asociación Latinoamericana de Patología Clínica/Medicina de Laboratorio

2009, Number 4

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Rev Mex Patol Clin Med Lab 2009; 56 (4)

Interference between medications and laboratory tests in hospitalized patients. An experience at the ABC Medical Center

Munive LMR, Simón DJI, Oropeza CR

Language: Spanish
References: 13
Page: 265-270
PDF size: 65.74 Kb.


ABSTRACT

Introduction: Hospitalized patients are generally under treatment with several drugs that may be capable of interfere with the methodologies used in laboratory tests. This situation may present a high risk of error and a challenge to laboratory professionals. Objective: To determine the interference frequency between medicines or drugs and laboratory tests in hospitalized patients. Material and methods: This was a prospective and observational study about the prescribed medications and the laboratory tests required to the hospitalized patients in the ABC Medical Center during the days of March 5th and 9th 2008. Results: The total number of patients hospitalized at the moment of the study was of 294, from which 219 of them (74.5%) counted on prescribed drugs. Thirty-four of these patients (17.8%) presented interference at the end of the study. The laboratory results and the medications found to be most frequently associated to interference were serum glucose andmetronidazole, respectively. Conclusions: The probability that a laboratory result may be affected by an interference phenomenon depends in a great part on the number and type of the administered drug or medication. This present study gives a general idea about the frequency that this phenomenon may present in our laboratory tests, and what kind of results may be potentially affected.


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