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2009, Number 3

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Neumol Cir Torax 2009; 68 (3)

Myocardial performance index in patients with obstructive sleep apnea syndrome

Carrillo AJL, Arredondo BFM, Reyes ZM, Sarabia OB, Yáñez GL, Torre BL, Castorena MA
Full text How to cite this article

Language: Spanish
References: 33
Page: 100-105
PDF size: 69.03 Kb.


Key words:

Apnea hypopnea index, myocardial performance index, obstructive sleep apnea syndrome.

ABSTRACT

Background: The myocardial performance index (MPI) is an echocardiographic measurement of the global myocardial function. The aim of this study was to measure the MPI of both the right (RV) and left ventricles (LV), and to explore the association between this index and the most important polysomnographic variables in patients with obstructive sleep apnea syndrome (OSAS). Methods: Patients over 18 years of age with OSAS were included. Patients with cardiac and pulmonary disease were excluded. Results: Ten patients were included (8 men and 2 women), median age was 50 years (minimum 34 - maximum 60), the median body mass index was 37 kg/m2 (30 - 39), and the apnea hypopnea index (AHI) was 77 events/hour (56 - 133). The median of the LV MPI was 0.64 (0.37 - 0.87), while that of the RV MPI was 0.57 (0.11 - 0.73). A significant association was found between the LV MPI and AHI (rs = 0.7, p = 0.01), and between the LV MPI and the respiratory arousal index (rs = 0.7, p = 0.02). Conclusions: Patients with severe obstructive sleep apnea syndrome have a biventricular myocardial dysfunction, this association depends on the severity of the OSAS and sleep fragmentation.


REFERENCES

  1. American Academy of Sleep Medicine. International classification of sleep disorders, 2nd Ed.: Diagnostic and coding manual. Wetchester, Illinois: American Academy of Sleep Medicine, 2005: 51.

  2. Young T, Palta M, Dempsey J, Skatrud J, Weber T, Badr S. The occurrence of sleep-disordered breathing mong middle-aged adults. N Engl J Med 1993; 328: 1230-1235.

  3. Torre BL, Vázquez GJC, Muiño A, Márquez M, et al. Prevalence of sleep-related symptoms in 4 Latin American cities. J Clin Sleep Med 2008; 4: 579-585.

  4. Flemons W. Obstructive Sleep Apnea. N Engl J Med 2002; 347: 498-504.

  5. Lavie P, Ben Yosef R, Rubin AE. Prevalence of sleep apnea syndrome among patients with essential hypertension. Am Heart J 1984; 108: 373-376.

  6. Hung J, Whitford EG, Parsons RW, Hillman DR. Association of sleep apnea with myocardial infarction in men. Lancet 1990; 336: 261-264.

  7. Palomaki H, Partinen M, Erkinjuntti I, Kaste M. Snoring, sleep apnea syndrome and stroke. Neurology 1992; 42: 75-82.

  8. Weitzenblum E, Krieger J, Apprill M, et al. Daytime pulmonary hypertension in patients with obstructive sleep apnea. Am Rev Respir Dis 1988; 138: 345-349.

  9. Guilleminault C, Connoly S, Winkle RA. Cardiac arrhythmia and conduction disturbances during sleep in 400 patients with sleep apnea syndrome. Am J Cardiol 1983; 52: 490-494.

  10. Malone S, Liu PP, Holloway R, Rutherford R, Xie A, Bradley TD. Obstructive sleep apnea in patients with dilated cardiomyopathy: Effects of CPAP. Lancet 1991; 338: 1480-1484.

  11. Torre-Bouscoulet L, Meza-Vargas S, Castorena-Maldonado A, Pérez-Padilla R. Riesgo cardiovascular en adultos con síndrome de apnea obstructiva del sueño. A 25 años de los primeros estudios de asociación. Gac Méd Méx 2008; 144: 323-332.

  12. Woodson T, Franco R. Physiology of Sleep Disordered Breathing. Otolaryngol Clin N Am 2007; 40: 691-711.

  13. Tei C, Ling L, Hodge D, et al. New index combined systolic and diastolic myocardial performance: A simple and reproducible measure of cardiac function: A study in normals and dilated cardiomyopathy. J Cardiol 1995; 26: 357-366.

  14. Marin JM, Carrizo SJ, Vicente E, et al. Long-term cardiovascular outcomes in men with obstructive sleep apnoea-hypopnoea with or without treatment with continuous positive airway pressure: an observational study. Lancet 2005; 365: 1046-1052.

  15. Flemons W, Whetelaw W, Brant R, Remers J. Likelihood ratios for sleep apnea clinical prediction rules. Am J Respir Crit Care Med 1994; 150: 1279-1285.

  16. Torre-Bouscoulet L, Chávez-Plascencia E, Vázquez-García JC, Pérez-Padilla R. Precisión y exactitud de un oxímetro de pulso «de bolsillo» en la ciudad de México. Rev Invest Clin 2006; 58: 28-33.

  17. Chica-Urzula H, Escobar-Córdoba F, Eslava-Schmalbach J. Validación de la escala de somnolencia de Epworth. Revista de Salud Pública 2007; 9: 558-567.

  18. Kushida C, Littner M, Morgenthafer T, et al. Practice parameters for the indication for polysomnography and related procedures: An Update for 2005. Sleep 2005; 28: 499-519.

  19. Schiller NB, Shah PM, Crawford M, et al. American Society of Echocardiography Committee on Standards, Subcommittee on quantitation of two-dimensional echocardiograms: Recommendations for quantitation of the left ventricle by two-dimensional echocardiography. J Am Soc Echocardiogr 1989; 2: 358-367.

  20. Teí C, Nishimon RA, Seward JB, Tajik AJ. Non-invasive Doppler derived myocardial performance index: correlation with simultaneous measurements of cardiac catheterization measurement. J Am Soc Echocardiography 1997; 10: 169-178.

  21. Slama M, Maizel J. Echocardiographic measurement of ventricular function. Curr Opin Crit Care 2006; 12: 241-248.

  22. Moro JA, Almenar L, Fernández-Fabrellas E, Ponce S, Blanquer R, Salvador A. Disfunción miocárdica silente en pacientes con síndrome de apneas-hipopneas durante el sueño. Valor del índice de rendimiento miocárdico. Arch Bronconeumol 2008; 44: 418-22.

  23. Koga S, Ikeda S, Urata J, Kohno S. Effect of nasal continuos positive airway pressure in men on global left ventricular myocardial performance in patients with obstructive sleep apnea syndrome. Am J Cardiol 2008; 101: 1796-1800.

  24. Dursunoglu N, Dursunoglu D, Özkurt S, Gur S, Ozalp G, Evyapan F. Effect of CPAP on right ventricular myocardial performance index in obstructive sleep apnea patients without hypertension. Respiratory Res 2006; doi:10.1186/1465-9921-7-22.

  25. Dursunoglu D, Dursunoglu N, Evregül H, et al. Impact of obstructive sleep apnoea on left ventricular mass and global function. Eur Respir J 2005; 26: 283-8.

  26. Dursunoglu N, Dursunoglu D, Özkurt D, et al. Effect of CPAP on left ventricular structure and myocardial performance index in male patients with obstructive sleep apnoea. Sleep Med 2007; 8: 51-59.

  27. Dursunoglu N, Dursunoglu D, Kilic M. Impact of Obstructive Sleep Apnea on Right Ventricular Global Function: Sleep Apnea and Myocardial Performance Index. Respiration 2005; 72: 278-284.

  28. Romero-Corral A, Somers V, Pellikka PA, et al. Decreased right and left ventricular myocardial performance in obstructive sleep apnea. Chest 2007; 132: 1863-70.

  29. Moro JA, Almenar L, Fernández-Fabrellas E, Ponce S, Blanquer R, Salvador A. Alteraciones ecocardiográficas asociadas al síndrome de apnea-hipopnea del sueño en función de su gravedad. Rev Esp Cardiol 2007; 60: 589-96.

  30. Tanvil Y, Kanbay A, Sen N, et al. Comparison of right ventricular functions by tissue Doppler imaging in patients with obstructive sleep apnea syndrome with or without hypertension. Int J Cardiovasc Imaging 2007; 23: 469-77.

  31. Bradley TD, Rutherford R, Grossman RF, et al. Role of daytime hypoxemia in the pathogenesis of right heart failure in the obstructive sleep apnea syndrome. Am Rev Respir Dis 1985; 131: 835-839.

  32. Dincer E, O´Neill W. Deletereous effects of sleep-disordered breathing on the heart and vascular system. Respiration 2006; 73: 124-130.

  33. Moro JA, Almenar L, Fernández-Fabrellas E, Ponce S, Blanquer R, Salvador A. Hypertension and sleep apnea-hypopnea syndrome: changes in echocardiographic abnormalities depending on the presence of hypertension and treatment with CPAP. Sleep Med 2009; 10: 344-52.




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Neumol Cir Torax. 2009;68