This journal only 2010, Number 1 Rev Mex Cir Bucal Maxilofac 2010; 6 (1) Unusual mandibular lesion of central odontogenic fibroma combinated with a central giant cells granuloma. Cortés CG, Liceaga RR, Mosqueda TA Full text How to cite this article Language: Spanish References: 21 Page: 19-24 PDF size: 209.92 Kb. Key words: Central odontogenic fibroma, hybrid lesion. ABSTRACT In few occasions we find two different lesions together in the jaw, but is still less common that one of those lesions one so uncommon as the central odontogenic fibroma. We present the case of a 14 years old patient with a osteolitic mandibular area that the histopathologic report showed a central odontogenic fibroma combinated with a central giant cells granuloma, with a great quantity of fibrocelular tissue highly vascularizated, with numerous dispersed multinucleated gigantic cells. REFERENCES Handlers JP, Abrams AM, Melrose RJ et al. Central odontogenic fibroma: Clinicopathologic features of 19 cases and review of the literature. J Oral Maxillofac Surg 1991; 49: 46. Kramer IRH, Pindborg JJ, Shear M. Histological typing of odontogenic tumor. Berlin Germany, Springer-Verlag, 1992. Calvo N, Alonso D, Prieto M, Junquera L. Central Odontogenic Fibroma Granular Cell Variant: A Case Report and Review of the Literature. J Oral Maxillofac Surg 2002; 60: 1192-1194. Gardner DG. The central odontogenic fibroma: An attempt at clarification. Oral Surg Oral Med Oral Path 1980; 01 (50): 425. Allen CM, Hammond HL, Stimson PG. Central odontogenic fibroma, WHO type: A report of three cases with an unusual associated giant cell reaction. Oral Surg Oral Med Oral Path 1992; 01: 73. Odell EW, Lombardi T, Barrett AW et al. Hybrid central giant cell granuloma and central odontogenic fibroma-lie lesions of the jaws. Histopathology 1997; 30: 165. Mosqueda TA, Bermúdez FV, Díaz FMA. Combined central odontogenic fibroma and giant cell granuloma-like lesion of the mandible: report of a case and review of the literature. J Oral Maxillofac Surg 1999; 57: 1258-l262. Kaffe I, Buchner, Buchner A. Radiologic features of central odontogenic fibroma. Oral Surg Oral Med Oral Pathol 1994; 78: 811. Spencer MJ. Daniels. Central odontogenic fibroma of mandible: a case report and review of the literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2004; 98: 295-300. Raubenheimer EJ, Noffke CE. Central odontogenic fibromalike tumors, hypodontia, and enamel dysplasia: review of the literature and report of a case. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2002; 94: 74-7. Zachariades N. Odontogenic fibroma. Int J Oral Maxillofac Surg 1986; 15: 102. de Lange J, van den Akker HP. Clinical and radiological features of central giant-cell lesions of the jaw. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2005; 99: 464-70. Chuong R, Kaban LB, Kozakewich H et al. Central giant cell lesions of the jaws: A clinicopathologic study. J Oral Maxillofac Surg 1986; 44: 708. Bataineh AB, Al-Khateeb T, Rawashdeh MA. The Surgical Treatment of Central Giant Cell Granuloma of the Mandible. J Oral Maxillofac Surg 2002; 60: 756-761. Whitaker SB, Waldron CA. Central giant cell lesions of the jaws. Oral Surg Oral Med Oral Pathol 1993; 75: 199. Cohen MA, Hertzanu Y. Radiologic features, including those seen with computed tomography, of central giant cell granuloma of the jaws. Oral Surg Oral Med Oral Pathol 1988; 65: 255. Webb DJ, Brockbank J. Combined curettage and cryosurgical treatment for the aggressive “giant cell lesion” of the mandible. Int J Oral Maxillofac Surg 1986; 5: 780. Eisenbud L, Stern M, Rothberg M et al. Central giant cell granuloma of the jaws: Experiences in the management of thirty-seven cases. J Oral Maxillofac Surg 1988; 46: 376-84. Harris M. Central giant cell granulomas of the jaws regress with calcitonin therapy. Br J Oral Maxillofac Surg 1993; 31: 89. de Lange J, Rosenberg AJ, van den Akker HP et al. Treatment of central giant cell granuloma of the jaw with calcitonin. Int J Oral Maxillofac Surg 1999; 28: 372. Kermer C, Millesi W, Watzke IM. Local injection of corticosteroids for central giant cell granuloma: A case report. Int J Oral Maxillofac Surg 1994;23: 366.