Galindo RME, Torres AP, Pérez HE, Gómez CG, Ruiz HJ

Language: Spanish
References: 10
Page: 105-110
PDF size: 362.83 Kb.

ABSTRACT

Introduction: In necropsies, the thyroid gland is not exhaustively researched, due to limitations in the number of histologic cuts or slices. This study described anatomopathologic findings in thyroid in 100 autopsies cases. Material and Methods: Thyroid glands from 100 autopsied cases of different age and sex were studied. Glands were fixed in 10 % formalin and sliced at 0.3-cm intervals for macroscopic examination; 3 to 8 sections per gland were included for histopathologic study. Four-microns cuts were staining with hematoxylin and eosin (H.E.) and reviewed by two pathologists. Results: There were 64 men and 36 women, ranging from newborns to 83-years-old. Forty six percent of cases were found between the third and fifth decade of life. Alterations were found in 52 cases. The most frequent alterations were benign: adenomatous nodular hyperplasia (34 %) and thyroiditis (14 %). Malignant lesions: three papillary microcarcinomas. Fifteen secondary lesions: septicemia and disseminated intravascular coagulation with fibrin thrombi were found in 12 cases, two patients with disseminated coccidioidomycosis were thyroiditis by the same agent, and there was one thyroid neurofibroma in a patient with neurofibromatosis. Conclusions: Thyroid pathology is frequent in our environment, as it was found in 52 % of cases. The most frequent alteration was benign: adenomatous nodular hyperplasia in 34 % of patients.

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