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>Journals >Cirugía y Cirujanos >Year 2010, Issue 3


Gallegos-Hernández JF
Abordaje diagnóstico-terapéutico del cáncer de mama asociado con embarazo. Actualización 2010
Cir Cir 2010; 78 (3)

Language: Español
References: 51
Page: 273-282
PDF: 287.04 Kb.

[Full text - PDF]

ABSTRACT

Breast cancer associated with pregnancy (defined as the presence of breast cancer during gestation extending until a year after the resolution of the pregnancy) represents controversial ethical dilemmas and contradictions in its diagnostic and therapeutic approach. Diagnostic methods and the role of pregnancy interruption are controversial subjects for prognosis. Our objective was to discuss the recommendations for diagnosis and treatment for these patients using evidence-based medicine and to discuss controversial subjects such as the role of lymphatic mapping, pre-therapeutic studies and appropriate treatment schedule. Fortunately, the prevalence of breast cancer during pregnancy is low. It is generally considered, however, that this prevalence will slowly increase because of two factors: 1) breast cancer is showing an increasing prevalence and 2) in Western societies the age when a woman becomes pregnant for the first time has increased, also associated with the age when breast cancer shows a higher frequency. As in the general population, breast cancer is the most frequent neoplasm in pregnant women. When diagnostic questions arise that sometimes do not have an answer based on scientific evidence, therapeutic decisions are often made based on knowledge acquired in breast cancer treatment of nonpregnant women. To routinely apply new diagnostic/therapeutic technologies with the safety of protecting the pregnancy is a difficult decision to make. In the end, the main objective of treatment of a pregnant woman with breast cancer is to maintain the standard of the desired oncological results while preserving the integrity of the fetus.


Key words: Breast cancer, pregnancy.


REFERENCES

  1. Peto R, Boreham J, Clarke M, Davies C, Beral UV. UK and USA breast cancer deaths down 25% in year 2000 at ages 20-69 years. Lancet 2000;355:1822.

  2. Cabrera-Gaytán DA, De la Rosa-Montaño BM, Kuri-Morales PA. Cáncer de mama en México: perfil epidemiológico a partir de los sistemas de información y vigilancia epidemiológica, 1998-2006. Gac Mex Oncol 2008;7:161-168.

  3. Aguayo-Alcaraz G, Jiménez-Pérez LM, Celis-De la Rosa A, Canales- Muñoz JL. Mortalidad por cáncer de mama. Tendencia y distribución geográfica, 1981-2001. Rev Med Inst Mex Seguro Soc 2008;46:367- 374.

  4. Antonelli, NM, Dotters, DJ, Katz, VL, Kuller JA. Cancer in pregnancy: a review of the literature. I. Obstet Gynecol Surv 1996;51:125.

  5. Woo JC, Yu, T, Hurd, TC. Breast cancer in pregnancy: a literature review. Arch Surg 2003;138:91-98.

  6. Scott-Conner CEH, Jochimsen PR, Sorosky JI. Breast cancer in pregnancy. In: Roses DF, ed. Breast Cancer. New York: Churchill Livingstone; 1999. p. 688.

  7. León-Villalba JC, López-Graniel CM, Lara-Medina F, Calderón GED, Chanona-Vilchis G, Solorza-Luna G. Cáncer y embarazo: experiencia en el Instituto Nacional de Cancerología. Rev Inst Nac Cancerol 1999;45:144-152.

  8. Ventura, SJ. First births to older mothers, 1970-86. Am J Public Health 1989;79:1675-1677.

  9. Theriault RL. Breast cancer during pregnancy. In: Singletary ES, Robb GL, eds. Advanced Therapy of Breast Disease. Hamilton: Decker; 2000. p. 344.

  10. Steiner RA. Gynecologic neoplasms in pregnancy. Terapeutische Umschau 1999;56:616.

  11. Holleb AI, Farrow JH. The relation of carcinoma of the breast and pregnancy in 283 patients. Surg Gynecol Obstet 1962;115:65.

  12. Gemignanni ML, Petreck JA, Borgen PI. Breast cancer and pregnancy. Surg Clin North Am 1999;79:1157.

  13. Fuentes-Alburo A, Chávez-McGregor R, Ramírez-Ugalde MT, De la Garza-Salazar JG. Early detection of breast cancer: who is responsible? 23rd Annual San Antonio Breast Cancer Symposium. Breast Cancer Res Treat 2000;64:250.

  14. Chiechi LM, Lobascio A, Loizzi P. Breast cancer in pregnancy. Resistance to screening. Minerva Ginecol 1998;50:301.

  15. Nettleton J, Long, J, Kuban, D, Wu R, Shaefffer, El-Mahdi A. Breast cancer during pregnancy: quantifying the risk of treatment delay. Obstet Gynecol 1996;87:414-418.

  16. Kline TS, Lash S. Nipple secretion in pregnancy: a cytologic and histologic study. Am J Clin Pathol 1962;37:626.

  17. Kline TS, Lash S. The bleeding nipple of pregnancy and postpartum. A cytologic and histologic study. Acta Cytol 1984;8:336

  18. Dietz JR, Kim JA, Dawson A. Phase 1 clinical trial of mammary ductoscopy in patients with pathologic nipple discharge. Breast Cancer Res Treat 2000;64:357.

  19. Dooley WC. Ductal lavage, nipple aspiration and ductoscopy for breast cancer diagnosis. Curr Oncol Rep 2003;5:63-65.

  20. Tondre J, Nejad M, Casano A, Mills D, Love S. Technical enhancements to breast ductal lavage. Ann Surg Oncol 2008;15:2734- 2738.

  21. Kapenhas-Valdes E, Feldman SM, Cohen JM, Boolbol SK. Mammary ductoscopy for evaluation of nipple discharge. Ann Surg Oncol 2008;15:2720-2727.

  22. Bass JE, Huynh PT. Imaging of the breast in pregnancy and lactation. In: Singletary ES, Robb GL eds. Advanced Therapy of Breast Disease. Hamilton: Decker; 2000. p. 344.

  23. Liberman L, Geiss C, Dershaw DD, Deutch BM, Petrek JA. Imaging of pregnancy-associated breast cancer. Radiology 1994;191:245-248.

  24. Kopans DB. Mammography and radiation risk. In: Janower ML, Linton OW, eds. Radiation Risk: A Primer. Reston, VA: American College of Radiology; 1996. pp. 21-22.

  25. 25 Ishida T, Yokoe T, Kasumi F, Sakamoto G, Makita M, Tominaga T. Clinicopathologic characteristics and prognosis of breast cancer patients associated with pregnancy and lactation: analysis of case-control study in Japan. Jpn J Cancer Res 1992;83:1143-1149.

  26. Yang, WT, Dryden, MJ, Gwyn, K, Whitman GJ, Theriault R. Imaging of breast cancer diagnosed and treated with chemotherapy during pregnancy. Radiology 2006;239:52-60.

  27. Stavros AT, Thickman D, Rapp CL, Dennis MA, Parker SH, Sisney GA. Solid breast nodules: use of sonography to distinguish between benign and malignant lesions. Radiology 1995;196:123-134.

  28. Lister D, Evans AJ, Burrell HC, Blamey RW, Wilson AR, Pinder SE, et al. The accuracy of breast ultrasound in the evaluation of clinically benign discrete, symptomatic breast lumps. Clin Radiol 1998;53:490- 492.

  29. Ahn BY, Kim, HH, Moon WK, Pisano ED, Kim HS, Cha ES, et al. Pregnancy and lactation-associated breast cancer: mammographic and sonographic findings. J Ultrasound Med 2003;22:491-497.

  30. Samuels TH, Liu FF, Yaffe M, Haider M. Gestational breast cancer. Can Assoc Radiol J 1998;49:172-180.

  31. Marchant DJ. Breast cancer in pregnancy. Clin Obstet Gynecol 1994;37:993-997.

  32. Talele AC, Slanetz, PJ, Edmister, WB, Yeh ED, Kopans DB. The lactating breast: MRI findings and literature review. Breast J 2003;9:237- 240.

  33. Cheek JH. Survey of current opinions concerning carcinoma of the breast occurring during pregnancy. Arch Surg 1953;66(5):664- 672.

  34. Daling JR, Malone KE, Voigt L, White E, Weiss NS. Risk of breast cancer among young women: relationship to induced abortion. J Natl Cancer Inst 1994;86:1584-1592.

  35. Behars OH, Henson DE, Hutter RVP and the American Joint Committee on Cancer. Manual for Staging of Breast Cancer, 3rd ed. Philadelphia: JB Lippincott; 1988. pp. 255-282.

  36. Kuerer HM, Gwyn K, Ames FC, Theriault RL. Conservative surgery and chemotherapy for breast carcinoma during pregnancy. Surgery 2002;131:108-110.

  37. Kuerer HM, Cunningham JD, Browser ST, Tartter PI. Breast carcinoma associated with pregnancy and lactation. Surg Oncol 1997;6:93-98.

  38. 38 National Comprehensive Cancer Network. Practice guidelines in oncology. V1.2009. Guidelines for the treatment of breast cancer during pregnancy. Preg1.

  39. Veronesi U, Paganelli G, Viale G, Luini A, Zurrida S, Galimberti V, et al. A randomized comparison of sentinel node biopsy with routine axillary dissection in breast cancer. N Engl J Med 2003;349;543-556.

  40. Gallegos-Hernández JF, Chávez-García MA. Utilidad del mapeo linfático con inyección subareolar de colorante azul patente V, en la etapificación del cáncer de mama. Rev Invest Clin 2003;55:407-411.

  41. Khera SY, Kiluk JV, Hasson DM, Meade TL, Meyers MP, Dupont EL, et al. Pregnancy-associated breast cancer patients can safely undergo lymphatic mapping. Breast J 2008;14:250-254.

  42. Mondi MM, Cuenca RE, Olila DW, Stewart JH 4th, Levine EA. Sentinel lymph node biopsy during initial clinical experience. Ann Surg Oncol 2007;14:218-221.

  43. Filippakis GM, Zografos G. Contraindications of sentinel lymph node biopsy: are there really? World J Surg Oncol 2007;29:5-10.

  44. Pandit-Taskar N, Dauer LT, Montgomery L, St Germain J, Zanzonico PB, Divgi CR. Organ and fetal absorbed dose estimates from 99mTcsulfur colloid lymphoscintigraphy and sentinel node localization in breast cancer patients. J Nucl Med 2006;47:1202-1208.

  45. Gentilini O, Masullo M, Rotmensz N, Peccatori F, Mazzarol G, Smeets A, et al. Breast cancer diagnosed during pregnancy and lactation: biological features and treatment options. Eur J Surg Oncol 2005;31:232-236.

  46. Berry DL, Theriault RL, Holmes, Booser DJ, Singletary SE, Buzdar AU, et al. Management of breast cancer during pregnancy using a standardized protocol. J Clin Oncol 1999;17:855-861.

  47. Blatt J, Mulvihill JJ, Ziegler JL, Young RC, Poplack DG. Pregnancy outcome following cancer chemotherapy. Am J Med 1980;69:828-832.

  48. Hudis CA, Norton L. Adjuvant therapy for breast cancer. In: Singletary ES, Robb GL, eds. Advanced Therapy of Breast Disease. Hamilton: Decker; 2000; p. 257.

  49. Cullins, SL, Pridjian, G, Sutherland CM. Goldenhar’s syndrome associated with tamoxifen given to the mother during gestation. JAMA 1994;271:1905.

  50. Loprinzi CH. Clinical issues regarding breast cancer and pregnancy. In: Wise L, Johnson H, eds. Breast Cancer. Controversies in Management. New York: Futura; 1994. p. 255

  51. Bonnier P, Romain S, Dilhuydy JM, Bonichon F, Julien JP, Charpin C, et al. Influence of pregnancy on the outcome of breast cancer: a case-control study. Societe Francaise de Senologie et de Pathologie Mammarie Study Group. Int J Cancer 1997;72:720-722.






>Journals >Cirugía y Cirujanos >Year 2010, Issue 3
 

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