Sánchez-Navarro MR, Moreno-López LC, Simón-Domínguez JI

Language: Spanish
References: 13
Page: 79-84
PDF size: 94.20 Kb.

ABSTRACT

The emergence and spread of antimicrobial resistant microorganisms is the cause of death in 17.5% in patients with bacteremia, varies by type of illness and age. In Mexico the main organism responsible for infections associated with healthcare are Pseudomonas aeruginosa and Escherichia coli, causing an overall case fatality in 36%. Objective. Establish the incidence of microorganisms causing bacteremia at The ABC Medical Center, and to evaluate variations in bacterial resistances to the usually prescribed antibiotics. Material and methods: Study from january 1st 2000 to december 31th 2007. Positive blood cultures were collected. We analyzed the number of isolated species per year basis, considering also the individual sensibility to antibiotics. With these data, the annual resistance per microorganism and per antibiotic was calculated. Results: Sixteen hundred and forty three isolates were analyzed in 1275 patients. The incidence of bacteremia was 11.3 per 1000 people admitted to hospital. The commonest microorganisms in the isolates were Escherichia coli with antimicrobial resistance from 30.9 to 41.9%, Pseudomonas aeruginosa with resistance from 26.7 to 62%, Enterococcus spp. with resistance from 36 to 46% and Staphylococcus aureus with resistance from 8 to 35%. Conclusions: The resistance per microorganism to antimicrobials in our institution is higher than that reported by others studies in Mexico. Our study will help clinicians in their decision making scheme to establish an early and adequate antimicrobial therapy.

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