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2006, Number 2

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Rev Mex Cir Pediatr 2006; 13 (2)

Diagnostic utility of percutaneous aspiration needle biopsy in a pediatric service

López-Ibarra S, Calderón-Elvir C, Braun-Roth G, Ridaura-Sanz C, Medina-Vega A
Full text How to cite this article

Language: Spanish
References: 8
Page: 69-72
PDF size: 132.77 Kb.


Key words:

Fine needle, Biopsy, Inmunohistoquimical, Tumor.

ABSTRACT

Introduction: There is no doubt that the citopayologic diagnosis of tumoral cels, of any origin in adults, by realizing an aspiration needle biopsy is a common practice and of high utility. However in a pediatric age is rarely done.
Material and methods: prospective, prolective , observational and comparative. Ultrasound was realized and or computed tomography to every patient with a high diagnosis of a solid tumor at the first consult. Afterwards de fine needle biopsy aspiration was done and an open biopsy at the surgical ward. Hematoxilin and eosin was applied to every biopsy , when there was doubt of the diagnosis Inmunohistoquimical studies were realized. Results were compared.
Results: Whe had 21 patients, 12 male and 9 female. Ages ranging from 1 day to 173 months, with a median of 67.6months. The anatomical site of the tumor was: abdominal in 9 cases, extremities in 5, and neck in 4, Thorax 1, pelvis 1, sacrococcigeal 1. In 3 patients (14.3%), the needle biopsy had no use excluding the following results( total of 18). To make a precise diagnosis of malignant tumors versus benign, the needle biopsy had a sensivity and specificity, negative and positive predictive value of 100%, similar to open biopsies. Eventhough to make a better diagnosis of malignancy, it diminished to a value of 38%( five patients). The open biopsy continued at 100%. When Inmunohistoquimical studies were realized to aspiration needle biopsy, the value was elevated to 100%.
Conclusion: the fine needle biopsy aspiration with the help of inmunohistoquimicalstudies offers a precise diagnosis in solid malignant tumors, giving good reasons to use fine needle biopsy aspiration biopsy as a first line diagnosis.


REFERENCES

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  3. Gross E, Lobe TE, Hoffer A, Look AT. Biopsy techniques for children with cancer. In: O’Neill JA Jr, Rowe MI, Grosfeld JL, Fonkalsrud EW, Coran AG. Pediatric Sugery, 5th edn. Mosby, St Louis, Mo, 1998 pp: 379-89

  4. Sklair LM, Daniel LP, Applbaum YH, Ramu N, et al. Percutaneous image-guided biopsy in children-summary of our experience with 57 children. Pediatr Radiol 2001;72: 732-36

  5. Hugosson CO, Nyman RS, Cappelen SJ, Akhtar M. Ultrasound-guided biopsy of abdominal and pelvic lesions in children. A comparison between fine-needle aspiration and 1.2 mm-needle core biopsy. Pediatr Radiol, 1999; 29: 31-36

  6. Hussain HK, Kingston JE, Domizio P, Norton AJ, Reznek RH. Imaging-guided core biopsy for the diagnosis of malignant tumors in pediatric patients. AJR, 2001; 176: 43-47

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  8. Braun RG, Calderón EC, Ruano AJ. Biopsia por aspiración con aguja delgada en pediatría. Acta Pediatr Mex, 1996; 17: 203-208




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Rev Mex Cir Pediatr. 2006;13